2. Gene
  3. PTER - phosphotriesterase related Gene

PTER - phosphotriesterase related Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as HPHRP; RPR-1

Gene ID: 9317 | Gene type: protein coding

About PTER

Cytogenetic location: 10p13 Genomic coordinates (GRCh38): 10:16,437,010-16,519,020 (from NCBI)

This gene has 5 transcripts (splice variants) and 205 orthologues. Ubiquitous expression in kidney (RPKM 11.0), brain (RPKM 10.8) and 25 other tissues.

Summary

Predicted to enable hydrolase activity, acting on ester bonds and zinc ion binding activity. Involved in epithelial cell differentiation. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

PTER Products(5)

mRNA Protein Name
NM_001001484.3 NP_001001484.1 phosphotriesterase-related protein isoform 1
NM_001261836.2 NP_001248765.1 phosphotriesterase-related protein isoform 1
NM_001261837.2 NP_001248766.1 phosphotriesterase-related protein isoform 2
NM_001261838.2 NP_001248767.1 phosphotriesterase-related protein isoform 3
NM_030664.5 NP_109589.2 phosphotriesterase-related protein isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence Reference Source
involved in epithelial cell differentiation IEP
IEP: Inferred from expression pattern
21492153 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PTER Protein Structure

PTE

PTE: Phosphotriesterase family (15 - 347)

  • 0
  • 100
  • 200
  • 300
  • 349 a.a.
Protein Preferred Names Protein Names

phosphotriesterase-related protein

parathion hydrolase-related protein

Related Diseases

Diseases Alias
Mucinous Bronchioloalveolar Adenocarcinoma

Bronchiolo-Alveolar Carcinoma, Mucinous
Dihydropyrimidinase Deficiency

Dihydropyrimidinuria

Dpys Deficiency

Dph Deficiency

DPYSD

Dihydrouracil Amidohydrolase Deficiency

Dihydropyrimidinuria Due To Dpys Deficiency
Bjornstad Syndrome

BJS

Pili Torti And Nerve Deafness

Ptd

Pili Torti-Deafness Syndrome

Deafness-Pili Torti-Hypogonadism Syndrome

Deafness And Pili Torti, Bjornstad Type

Pili Torti-Sensorineural Hearing Loss

Björnstad Syndrome

Ptnd

Hearing Loss-Pili Torti-Hypogonadism Syndrome

Bjoernstad Syndrome
Secondary Syphilis

Syphilis, Secondary

Secondary Syphilis Of Viscera Or Bone
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-157126 Pterostilbene-isothiocyanate Inhibitor / Unkown
HY-RS11366 PTER Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus PTER VGNC VGNC:69140
Rattus norvegicus PTER RGD RGD:61313
Mus musculus PTER MGD MGI:107372
Canis familiaris PTER VGNC VGNC:45139
Macaca mulatta PTER VGNC VGNC:76466
Bos taurus PTER VGNC VGNC:33497
Others PTER NCBI