2. Gene
  3. Cadm3 - cell adhesion molecule 3 Gene

Cadm3 - cell adhesion molecule 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as BIgR; Necl1; Tsll1; Igsf4b; Necl-1; SynCAM3

Gene ID: 94332 | Gene type: protein coding

About Cadm3

Summary

Enables protein homodimerization activity. Involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules and homophilic cell adhesion via plasma membrane adhesion molecules. Acts upstream of or within protein localization. Located in cell-cell junction and parallel fiber to Purkinje cell synapse. Is integral component of presynaptic membrane. Is expressed in several structures, including intestine; liver; nervous system; neural retina; and olfactory epithelium. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease. Orthologous to human CADM3 (cell adhesion molecule 3). [provided by Alliance of Genome Resources, Apr 2022]

Cadm3 Products(3)

mRNA Protein Name
NM_001412814.1 NP_001399743.1 cell adhesion molecule 3 isoform 1 precursor
NM_001412815.1 NP_001399744.1 cell adhesion molecule 3 isoform 2
NM_053199.4 NP_444429.1 cell adhesion molecule 3 isoform 3 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
15893517 MGI
enables protein homodimerization activity IPI
IPI: Inferred from physical interaction
12826663 MGI
Biological Process GO Annotation Evidence Reference Source
involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IDA
IDA: Inferred from direct assay
12826663 MGI
involved in homophilic cell adhesion via plasma membrane adhesion molecules IDA
IDA: Inferred from direct assay
12826663 MGI
acts upstream of or within protein localization IMP
IMP: Inferred from mutant phenotype
15893517 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cell-cell junction IDA
IDA: Inferred from direct assay
15893517 MGI
is active in parallel fiber to Purkinje cell synapse IDA
IDA: Inferred from direct assay
15741237 MGI
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
15741237 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cell adhesion molecule 3

TSLC1-like protein 1

immunoglobulin superfamily, member 4B

nectin-like protein 1

nectin-lke 1

synaptic cell adhesion molecule 3

Recombinant Cadm3 Proteins

Cat. No. Product Name Accession Purity
HY-P76756 CADM3 Protein, Mouse (HEK293, His) Q99N28 (N23-H328) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01821 CADM3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cadm3 NCBI NCBI:57863
Macaca fascicularis Cadm3 NCBI NCBI:102129491
Rattus norvegicus Cadm3 NCBI NCBI:360882