2. Cell Cycle/DNA Damage
  3. Deubiquitinase
  4. GK16S

GK16S is a UCHL1 chemogenomic probe. GK16S can be used as a complement to GK13S. GK16S and GK13S can be used to study UCHL1 function in cells. GK16S is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

For research use only. We do not sell to patients.

GK16S Chemical Structure

GK16S Chemical Structure

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5 mg USD 140 In-stock
10 mg USD 225 In-stock
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Based on 1 publication(s) in Google Scholar

GK16S Related Antibodies

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USP1 USP2 USP7 USP8 USP30 UCHL1

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Description

GK16S is a UCHL1 chemogenomic probe. GK16S can be used as a complement to GK13S. GK16S and GK13S can be used to study UCHL1 function in cells[1]. GK16S is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Molecular Weight

205.26

Formula

C11H15N3O
Appearance

Oil

Color

Colorless to light yellow

SMILES

C#CCCCNC([C@H]1CCN(C#N)C1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (487.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.8719 mL 24.3594 mL 48.7187 mL
5 mM 0.9744 mL 4.8719 mL 9.7437 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.8719 mL 24.3593 mL 48.7187 mL 121.7967 mL
5 mM 0.9744 mL 4.8719 mL 9.7437 mL 24.3593 mL
10 mM 0.4872 mL 2.4359 mL 4.8719 mL 12.1797 mL
15 mM 0.3248 mL 1.6240 mL 3.2479 mL 8.1198 mL
20 mM 0.2436 mL 1.2180 mL 2.4359 mL 6.0898 mL
25 mM 0.1949 mL 0.9744 mL 1.9487 mL 4.8719 mL
30 mM 0.1624 mL 0.8120 mL 1.6240 mL 4.0599 mL
40 mM 0.1218 mL 0.6090 mL 1.2180 mL 3.0449 mL
50 mM 0.0974 mL 0.4872 mL 0.9744 mL 2.4359 mL
60 mM 0.0812 mL 0.4060 mL 0.8120 mL 2.0299 mL
80 mM 0.0609 mL 0.3045 mL 0.6090 mL 1.5225 mL
100 mM 0.0487 mL 0.2436 mL 0.4872 mL 1.2180 mL
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GK16S Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GK16SDeubiquitinaseDUBsChemogenomicUCHL1 probeGK13SInhibitorinhibitorinhibit

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