2. Metabolic Enzyme/Protease Anti-infection
  3. Aminoacyl-tRNA Synthetase Bacterial
  4. Glu-AMS TEA

Glu-AMS TEA is a competitive inhibitor of Escherichia coli glutamyl-tRNA synthetase (GluRS), with the Ki of 2.8 nM.

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Glu-AMS TEA Chemical Structure

Glu-AMS TEA Chemical Structure

CAS No. : 1810728-44-9

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10 mg USD 1100 In-stock
25 mg USD 2200 In-stock
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Glu-AMS TEA Related Antibodies

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Description

Glu-AMS TEA is a competitive inhibitor of Escherichia coli glutamyl-tRNA synthetase (GluRS), with the Ki of 2.8 nM[1].

Molecular Weight

576.62

Formula

C21H36N8O9S
CAS No.
Appearance

Solid

SMILES

CCN(CC)CC.O[C@H]1[C@@H](O)[C@H](N2C=NC3=C(N)N=CN=C32)O[C@@H]1COS(NC([C@@H](N)CCC(O)=O)=O)(=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (173.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7342 mL 8.6712 mL 17.3424 mL
5 mM 0.3468 mL 1.7342 mL 3.4685 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7342 mL 8.6712 mL 17.3424 mL 43.3561 mL
5 mM 0.3468 mL 1.7342 mL 3.4685 mL 8.6712 mL
10 mM 0.1734 mL 0.8671 mL 1.7342 mL 4.3356 mL
15 mM 0.1156 mL 0.5781 mL 1.1562 mL 2.8904 mL
20 mM 0.0867 mL 0.4336 mL 0.8671 mL 2.1678 mL
25 mM 0.0694 mL 0.3468 mL 0.6937 mL 1.7342 mL
30 mM 0.0578 mL 0.2890 mL 0.5781 mL 1.4452 mL
40 mM 0.0434 mL 0.2168 mL 0.4336 mL 1.0839 mL
50 mM 0.0347 mL 0.1734 mL 0.3468 mL 0.8671 mL
60 mM 0.0289 mL 0.1445 mL 0.2890 mL 0.7226 mL
80 mM 0.0217 mL 0.1084 mL 0.2168 mL 0.5420 mL
100 mM 0.0173 mL 0.0867 mL 0.1734 mL 0.4336 mL
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Glu-AMS TEA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Glu-AMS1810728-44-9Aminoacyl-tRNA SynthetaseBacterialtRNA Synthetase, aaRSE. coliInhibitorinhibitorinhibit

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