Glucocorticoid receptor modulator 2

Cat. No.: HY-149165 Purity: 99.84%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Glucocorticoid receptor modulator 2 (Example 1) is a glucocorticoid receptor modulator, with an IC₅₀ value less than 100 nM. Glucocorticoid receptor modulator 2 can be used for research of inflammatory and immune diseases.

For research use only. We do not sell to patients.

Glucocorticoid receptor modulator 2 Chemical Structure

CAS No. : 2452396-89-1

Size	Price	Stock	Quantity
1 mg	USD 110	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 260	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 390	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

Molecular Weight

482.55

Formula

C₂₉H₂₇FN₄O₂

CAS No.

2452396-89-1

Appearance

Solid

Color

Light brown to brown

SMILES

O=C(C1CC1)N[C@@H]2[C@@H](C3=CC=CC=C3)N(C4=CC=C(N(C5=CC=C(C=C5)F)N=C6)C6=C4)C(C2(C)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (259.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0723 mL	10.3616 mL	20.7232 mL
5 mM	0.4145 mL	2.0723 mL	4.1446 mL
10 mM	0.2072 mL	1.0362 mL	2.0723 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Dosing volume
(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.84%

Select Batch:

Data Sheet (276 KB) SDS (251 KB)

COA (261 KB) HNMR (287 KB) LCMS (91 KB)

Handling Instructions (2659 KB)

References

[1]. Florian JAKOB, et al. Substituted pyrrolidine amides iii. Patent. WO2020144375.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.0723 mL	10.3616 mL	20.7232 mL	51.8081 mL
	5 mM	0.4145 mL	2.0723 mL	4.1446 mL	10.3616 mL
	10 mM	0.2072 mL	1.0362 mL	2.0723 mL	5.1808 mL
	15 mM	0.1382 mL	0.6908 mL	1.3815 mL	3.4539 mL
	20 mM	0.1036 mL	0.5181 mL	1.0362 mL	2.5904 mL
	25 mM	0.0829 mL	0.4145 mL	0.8289 mL	2.0723 mL
	30 mM	0.0691 mL	0.3454 mL	0.6908 mL	1.7269 mL
	40 mM	0.0518 mL	0.2590 mL	0.5181 mL	1.2952 mL
	50 mM	0.0414 mL	0.2072 mL	0.4145 mL	1.0362 mL
	60 mM	0.0345 mL	0.1727 mL	0.3454 mL	0.8635 mL
	80 mM	0.0259 mL	0.1295 mL	0.2590 mL	0.6476 mL
	100 mM	0.0207 mL	0.1036 mL	0.2072 mL	0.5181 mL