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Glycyl-glutamine  (Synonyms: Glycyl-L-glutamine)

Cat. No.: HY-117541 Purity: ≥98.0%
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Glycyl-glutamine (Glycyl-L-glutamine), as a enzymatic cleavage product of β-endorphin, is apparently an endogenous antagonist of beta-endorphin(1-31) in several systems. Glycyl-glutamine (Glycyl-L-glutamine) is an activate and stable glutamine-containing neuropeptide over glutamine (Gln).

For research use only. We do not sell to patients.

Glycyl-glutamine Chemical Structure

Glycyl-glutamine Chemical Structure

CAS No. : 13115-71-4

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 USD 41 In-stock
Solution
10 mM * 1 mL in Water USD 41 In-stock
Solid
50 mg USD 38 In-stock
100 mg USD 60 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Glycyl-glutamine Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Glycyl-glutamine (Glycyl-L-glutamine), as a enzymatic cleavage product of β-endorphin, is apparently an endogenous antagonist of beta-endorphin(1-31) in several systems[1]. Glycyl-glutamine (Glycyl-L-glutamine) is an activate and stable glutamine-containing neuropeptide over glutamine (Gln)[2].

In Vitro

Glycyl-glutamine (Glycyl-L-glutamine) is an activate and stable glutamine-containing neuropeptide. Glycyl-glutamine (Glycyl-L-glutamine) has an advantage over free glutamine (Gln)  as growth factors for cell culture during both autoclaving and storage[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Glycyl-glutamine Related Antibodies
In Vivo

Glycyl-glutamine (Glycyl-L-glutamine) (0.3, 0.6, 1.0 and 10.0 nM) can dose-dependently inhibit beta-End-(1-31)-induced hypotension in pentobarbital-anesthetized rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

203.20

Formula

C7H13N3O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C([C@H](CCC(N)=O)NC(CN)=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

H2O : 62.5 mg/mL (307.58 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.9213 mL 24.6063 mL 49.2126 mL
5 mM 0.9843 mL 4.9213 mL 9.8425 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (492.13 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.9213 mL 24.6063 mL 49.2126 mL 123.0315 mL
5 mM 0.9843 mL 4.9213 mL 9.8425 mL 24.6063 mL
10 mM 0.4921 mL 2.4606 mL 4.9213 mL 12.3031 mL
15 mM 0.3281 mL 1.6404 mL 3.2808 mL 8.2021 mL
20 mM 0.2461 mL 1.2303 mL 2.4606 mL 6.1516 mL
25 mM 0.1969 mL 0.9843 mL 1.9685 mL 4.9213 mL
30 mM 0.1640 mL 0.8202 mL 1.6404 mL 4.1010 mL
40 mM 0.1230 mL 0.6152 mL 1.2303 mL 3.0758 mL
50 mM 0.0984 mL 0.4921 mL 0.9843 mL 2.4606 mL
60 mM 0.0820 mL 0.4101 mL 0.8202 mL 2.0505 mL
80 mM 0.0615 mL 0.3076 mL 0.6152 mL 1.5379 mL
100 mM 0.0492 mL 0.2461 mL 0.4921 mL 1.2303 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Glycyl-glutamine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Glycyl-glutamine13115-71-4Glycyl-L-glutamineOthershypotensionneuropeptideInhibitorinhibitorinhibit

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