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  4. Glycylglycylcysteine

Glycylglycylcysteine is a Thrombin Activatable Fibrinolysis Inhibitor (TAFI) inhibitor with a Ki of 0.99 μM and a IC50 of 9.4 μM in TAFI substrate assays. TAFI is a basic carboxypeptidase that functions as a fibrinolysis inhibitor through the cleavage of C-terminal lysine on partially degraded fibrin.

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Glycylglycylcysteine Chemical Structure

Glycylglycylcysteine Chemical Structure

CAS No. : 95416-30-1

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Description

Glycylglycylcysteine is a Thrombin Activatable Fibrinolysis Inhibitor (TAFI) inhibitor with a Ki of 0.99 μM and a IC50 of 9.4 μM in TAFI substrate assays. TAFI is a basic carboxypeptidase that functions as a fibrinolysis inhibitor through the cleavage of C-terminal lysine on partially degraded fibrin[1].

IC50 & Target

IC50: 9.4 μM (TAFI)
Ki: 0.99 μM (TAFI)[1]

Molecular Weight

235.26

Formula

C7H13N3O4S

CAS No.
Sequence

H-Gly-Gly-Cys-OH

Sequence Shortening

GGK

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Glycylglycylcysteine
Cat. No.:
HY-P4269
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