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  3. Glyphosate-13C2,15N

Glyphosate-13C2,15N is the 13C and 15N labled Glyphosate (HY-B0863). Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants.

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Glyphosate-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N Chemical Structure

Glyphosate-13C2,15N Chemical Structure

CAS No. : 1185107-63-4

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Based on 1 publication(s) in Google Scholar

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Description

Glyphosate-13C2,15N is the 13C and 15N labled Glyphosate (HY-B0863). Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

172.05

Formula

C13C2H815NO5P

CAS No.
Unlabeled CAS

1071-83-6

Appearance

Solid

Color

White to off-white

SMILES

O=[13C](O)[13CH2][15NH]CP(O)(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 13.89 mg/mL (80.73 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.8123 mL 29.0613 mL 58.1226 mL
5 mM 1.1625 mL 5.8123 mL 11.6245 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.8123 mL 29.0613 mL 58.1226 mL 145.3066 mL
5 mM 1.1625 mL 5.8123 mL 11.6245 mL 29.0613 mL
10 mM 0.5812 mL 2.9061 mL 5.8123 mL 14.5307 mL
15 mM 0.3875 mL 1.9374 mL 3.8748 mL 9.6871 mL
20 mM 0.2906 mL 1.4531 mL 2.9061 mL 7.2653 mL
25 mM 0.2325 mL 1.1625 mL 2.3249 mL 5.8123 mL
30 mM 0.1937 mL 0.9687 mL 1.9374 mL 4.8436 mL
40 mM 0.1453 mL 0.7265 mL 1.4531 mL 3.6327 mL
50 mM 0.1162 mL 0.5812 mL 1.1625 mL 2.9061 mL
60 mM 0.0969 mL 0.4844 mL 0.9687 mL 2.4218 mL
80 mM 0.0727 mL 0.3633 mL 0.7265 mL 1.8163 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Glyphosate-13C2,15N
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HY-B0863S3
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