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  3. Gold(III) chloride trihydrate

Gold (III) chloride trihydrate is a reducing agent. Gold (III) chromium trihydrate can be used for chemical synthesis of gold nanoparticles (NP) and spirochromene derivatives.

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Gold(III) chloride trihydrate Chemical Structure

Gold(III) chloride trihydrate Chemical Structure

CAS No. : 16961-25-4

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Description

Gold (III) chloride trihydrate is a reducing agent. Gold (III) chromium trihydrate can be used for chemical synthesis of gold nanoparticles (NP) and spirochromene derivatives[1][2].

In Vitro

Gold nanoparticle synthesis method[1]:
1. Prepare a 2.5 mM HAuCl4·3H2O solution by mixing 0.05 g of Gold(III) chloride trihydrate with 50 mL of deionized water.
2. Prepare a 6.6 mM sodium hydroxide (NaOH) solution by mixing 0.0264 g of NaOH with 100 mL of deionized water.
3. Control the pH of 10 mL of HAuCl4·3H2O solution by adding NaOH until the pH reaches 6.6. This process heats the solution to 85 °C for 30 minutes under vigorous stirring.
4. Prepare a 5 mM sodium citrate (C6H5Na3O7) solution by mixing 0.073 g of sodium citrate with 50 mL of deionized water.
5. Heat 10 mL of sodium citrate solution to about 85°C for about 20 minutes and add HAuCl4·3H2O solution after vigorous stirring to obtain a deep red gold nanoparticle solution.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

393.83

Formula

HAuCl4.3H2O

CAS No.
Appearance

Solid

Color

Yellow to orange

SMILES

[H+].[Cl-][Au+3]([Cl-])([Cl-])[Cl-].O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature, keep dry and cool

In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

H2O : 150 mg/mL (380.87 mM; Need ultrasonic and warming)

DMSO : 100 mg/mL (253.92 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5392 mL 12.6958 mL 25.3917 mL
5 mM 0.5078 mL 2.5392 mL 5.0783 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥99.9%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 2.5392 mL 12.6958 mL 25.3917 mL 63.4792 mL
5 mM 0.5078 mL 2.5392 mL 5.0783 mL 12.6958 mL
10 mM 0.2539 mL 1.2696 mL 2.5392 mL 6.3479 mL
15 mM 0.1693 mL 0.8464 mL 1.6928 mL 4.2319 mL
20 mM 0.1270 mL 0.6348 mL 1.2696 mL 3.1740 mL
25 mM 0.1016 mL 0.5078 mL 1.0157 mL 2.5392 mL
30 mM 0.0846 mL 0.4232 mL 0.8464 mL 2.1160 mL
40 mM 0.0635 mL 0.3174 mL 0.6348 mL 1.5870 mL
50 mM 0.0508 mL 0.2539 mL 0.5078 mL 1.2696 mL
60 mM 0.0423 mL 0.2116 mL 0.4232 mL 1.0580 mL
80 mM 0.0317 mL 0.1587 mL 0.3174 mL 0.7935 mL
100 mM 0.0254 mL 0.1270 mL 0.2539 mL 0.6348 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Gold(III) chloride trihydrate
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