GR65630

Cat. No.: HY-164083: FAQs
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GR65630 is a potent and selective 5-hydroxytryptamine (5-HT) type 3 receptor antagonist. GR65630 can be used to study the expression patterns of 5-HT3 receptors in different brain regions and their possible functions in the central nervous system. GR65630 and its radiolabeled form [³H]GR65630 can be used to study the distribution, density and affinity of the receptors.

For research use only. We do not sell to patients.

GR65630 Chemical Structure

CAS No. : 113140-33-3

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5-HT₁ Receptor 5-HT₂ Receptor 5-HT₃ Receptor 5-HT₄ Receptor 5-HT₅ Receptor 5-HT₆ Receptor 5-HT₇ Receptor 5-HT Receptor

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Description	GR65630 is a potent and selective 5-hydroxytryptamine (5-HT) type 3 receptor antagonist. GR65630 can be used to study the expression patterns of 5-HT3 receptors in different brain regions and their possible functions in the central nervous system. GR65630 and its radiolabeled form [³H]GR65630 can be used to study the distribution, density and affinity of the receptors^[1].
Molecular Weight	267.33
Formula	C₁₆H₁₇N₃O
CAS No.	113140-33-3
SMILES	O=C(CCC1=C(C)N=CN1)C2=CN(C)C3=C2C=CC=C3
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (270 KB) Handling Instructions (2659 KB)
References	[1]. Kilpatrick G J, et al. Binding of the 5-HT3 ligand,[3H] GR65630, to rat area postrema, vagus nerve and the brains of several species[J]. European journal of pharmacology, 1989, 159(2): 157-164. [Content Brief]

GR65630 Related Classifications

Neurological Disease

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GR65630113140-33-3GR 65630GR-656305-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorAntagonistCentral nervous systemRadiolabeling5-HTInhibitorinhibitorinhibit

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GR65630

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