2. GPCR/G Protein
  3. Free Fatty Acid Receptor
  4. Grifolic acid

Grifolic acid is a phenolic compound that is first extracted from the mushroom Albatrellus confluens. Grifolic acid acts as an agonist of the free fatty acid receptor (FFAR4/GPR120).

For research use only. We do not sell to patients.

Grifolic acid Chemical Structure

Grifolic acid Chemical Structure

CAS No. : 80557-12-6

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Based on 1 publication(s) in Google Scholar

Grifolic acid Related Antibodies

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Description

Grifolic acid is a phenolic compound that is first extracted from the mushroom Albatrellus confluens. Grifolic acid acts as an agonist of the free fatty acid receptor (FFAR4/GPR120)[1].

In Vitro

Grifolic acid (2.5-20 μM) treatment reduces RAW264.7 cell viability in a dose and time dependent manner[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Grifolic acid Related Antibodies
Molecular Weight

372.50

Formula

C23H32O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C1=C(C)C=C(O)C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)=C1O
Structure Classification
Initial Source

fungus Albatrellus confluens
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (268.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6846 mL 13.4228 mL 26.8456 mL
5 mM 0.5369 mL 2.6846 mL 5.3691 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6846 mL 13.4228 mL 26.8456 mL 67.1141 mL
5 mM 0.5369 mL 2.6846 mL 5.3691 mL 13.4228 mL
10 mM 0.2685 mL 1.3423 mL 2.6846 mL 6.7114 mL
15 mM 0.1790 mL 0.8949 mL 1.7897 mL 4.4743 mL
20 mM 0.1342 mL 0.6711 mL 1.3423 mL 3.3557 mL
25 mM 0.1074 mL 0.5369 mL 1.0738 mL 2.6846 mL
30 mM 0.0895 mL 0.4474 mL 0.8949 mL 2.2371 mL
40 mM 0.0671 mL 0.3356 mL 0.6711 mL 1.6779 mL
50 mM 0.0537 mL 0.2685 mL 0.5369 mL 1.3423 mL
60 mM 0.0447 mL 0.2237 mL 0.4474 mL 1.1186 mL
80 mM 0.0336 mL 0.1678 mL 0.3356 mL 0.8389 mL
100 mM 0.0268 mL 0.1342 mL 0.2685 mL 0.6711 mL
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Grifolic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Grifolic acid80557-12-6Free Fatty Acid ReceptorFFARanti inflammatoryeffectmacrophagecelldeathATPRAW264.7Inhibitorinhibitorinhibit

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