2. Anti-infection
  3. HCV
  4. GS-6620

GS-6620 is potent and selective pangenotype HCV inhibitor against HCV replicons of genotypes 1 to 6 (EC50: 0.048 to 0.68 μM). GS-6620 shows limited activities against other viruses, maintaining only some of its activity against the closely related bovine viral diarrhea virus (EC50, 1.5 μM).

For research use only. We do not sell to patients.

GS-6620 Chemical Structure

GS-6620 Chemical Structure

CAS No. : 1350735-70-4

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Based on 1 publication(s) in Google Scholar

GS-6620 Related Antibodies

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Description

GS-6620 is potent and selective pangenotype HCV inhibitor against HCV replicons of genotypes 1 to 6 (EC50: 0.048 to 0.68 μM). GS-6620 shows limited activities against other viruses, maintaining only some of its activity against the closely related bovine viral diarrhea virus (EC50, 1.5 μM)[1].

IC50 & Target

IC50: 48-680 nM (HCV replicons of genotypes 1 to 6)[1]
Molecular Weight

644.61

Formula

C29H37N6O9P
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

N#C[C@](O[C@@H]1CO[P@](OC2=CC=CC=C2)(N[C@@H](C)C(OC(C)C)=O)=O)(C3=CC=C4N3N=CN=C4N)[C@](O)([C@@H]1OC(C(C)C)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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GS-6620 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GS-66201350735-70-4GS6620GS 6620HCVHepatitis C virusInhibitorinhibitorinhibit

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