2. GPCR/G Protein
  3. Urotensin Receptor
  4. GSK 1562590 hydrochloride

GSK 1562590 hydrochloride is a high affinity and selective antagonist of urotensin-II receptor (UT), with pKis of 9.14-9.66 for mammalian recombinant (mouse, rat, cat, monkey, human) and native UT.

For research use only. We do not sell to patients.

GSK 1562590 hydrochloride Chemical Structure

GSK 1562590 hydrochloride Chemical Structure

CAS No. : 1003878-07-6

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10 mg USD 1184 Get quote 2 - 3 weeks 4 - 5 weeks 1 - 2 weeks
50 mg USD 3552 Get quote 2 - 3 weeks 4 - 5 weeks 1 - 2 weeks
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Based on 1 publication(s) in Google Scholar

GSK 1562590 hydrochloride Related Antibodies

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Description

GSK 1562590 hydrochloride is a high affinity and selective antagonist of urotensin-II receptor (UT), with pKis of 9.14-9.66 for mammalian recombinant (mouse, rat, cat, monkey, human) and native UT[1].

Molecular Weight

617.95

Formula

C30H31Cl3N4O4
CAS No.
SMILES

O=C(N([C@H](C1=CC=C(C2=CC=CC(C(N)=O)=C2)C=C1)CN3CCCC3)C)CN4C(COC5=CC(Cl)=C(Cl)C=C45)=O.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 61.8 mg/mL (100.01 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6183 mL 8.0913 mL 16.1825 mL
5 mM 0.3237 mL 1.6183 mL 3.2365 mL
View the Complete Stock Solution Preparation Table

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6183 mL 8.0913 mL 16.1825 mL 40.4563 mL
5 mM 0.3237 mL 1.6183 mL 3.2365 mL 8.0913 mL
10 mM 0.1618 mL 0.8091 mL 1.6183 mL 4.0456 mL
15 mM 0.1079 mL 0.5394 mL 1.0788 mL 2.6971 mL
20 mM 0.0809 mL 0.4046 mL 0.8091 mL 2.0228 mL
25 mM 0.0647 mL 0.3237 mL 0.6473 mL 1.6183 mL
30 mM 0.0539 mL 0.2697 mL 0.5394 mL 1.3485 mL
40 mM 0.0405 mL 0.2023 mL 0.4046 mL 1.0114 mL
50 mM 0.0324 mL 0.1618 mL 0.3237 mL 0.8091 mL
60 mM 0.0270 mL 0.1349 mL 0.2697 mL 0.6743 mL
80 mM 0.0202 mL 0.1011 mL 0.2023 mL 0.5057 mL
100 mM 0.0162 mL 0.0809 mL 0.1618 mL 0.4046 mL
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GSK 1562590 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GSK 15625901003878-07-6GSK1562590GSK-1562590Urotensin ReceptorUT receptorInhibitorinhibitorinhibit

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