2. GPCR/G Protein
  3. Urotensin Receptor
  4. GSK 1562590 hydrochloride

GSK 1562590 hydrochloride is a high affinity and selective antagonist of urotensin-II receptor (UT), with pKis of 9.14-9.66 for mammalian recombinant (mouse, rat, cat, monkey, human) and native UT.

For research use only. We do not sell to patients.

GSK 1562590 hydrochloride Chemical Structure

GSK 1562590 hydrochloride Chemical Structure

CAS No. : 1003878-07-6

Size Price Stock Quantity
1 mg USD 296 In-stock
5 mg USD 740 In-stock
10 mg USD 1184 In-stock
50 mg USD 3552 Get quote
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

GSK 1562590 hydrochloride Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

GSK 1562590 hydrochloride is a high affinity and selective antagonist of urotensin-II receptor (UT), with pKis of 9.14-9.66 for mammalian recombinant (mouse, rat, cat, monkey, human) and native UT[1].

Molecular Weight

617.95

Formula

C30H31Cl3N4O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N([C@H](C1=CC=C(C2=CC=CC(C(N)=O)=C2)C=C1)CN3CCCC3)C)CN4C(COC5=CC(Cl)=C(Cl)C=C45)=O.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 61.8 mg/mL (100.01 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6183 mL 8.0913 mL 16.1825 mL
5 mM 0.3237 mL 1.6183 mL 3.2365 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6183 mL 8.0913 mL 16.1825 mL 40.4563 mL
5 mM 0.3237 mL 1.6183 mL 3.2365 mL 8.0913 mL
10 mM 0.1618 mL 0.8091 mL 1.6183 mL 4.0456 mL
15 mM 0.1079 mL 0.5394 mL 1.0788 mL 2.6971 mL
20 mM 0.0809 mL 0.4046 mL 0.8091 mL 2.0228 mL
25 mM 0.0647 mL 0.3237 mL 0.6473 mL 1.6183 mL
30 mM 0.0539 mL 0.2697 mL 0.5394 mL 1.3485 mL
40 mM 0.0405 mL 0.2023 mL 0.4046 mL 1.0114 mL
50 mM 0.0324 mL 0.1618 mL 0.3237 mL 0.8091 mL
60 mM 0.0270 mL 0.1349 mL 0.2697 mL 0.6743 mL
80 mM 0.0202 mL 0.1011 mL 0.2023 mL 0.5057 mL
100 mM 0.0162 mL 0.0809 mL 0.1618 mL 0.4046 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

GSK 1562590 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GSK 15625901003878-07-6GSK1562590GSK-1562590Urotensin ReceptorUT receptorInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
GSK 1562590 hydrochloride
Cat. No.:
HY-108446
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (251 KB) Français - FR (251 KB) Deutsch - DE (251 KB) Norwegian - NO (251 KB) Español - ES (251 KB) Swedish - SV (251 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.