GSK-J2 sodium

Cat. No.: HY-15648I: FAQs
Data Sheet Handling Instructions

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GSK-J2 sodium is the sodium form of GSK-J2 (HY-15648A). GSK-J2 is an isomer of GSK-J1, and does not have any specific activity. GSK-J1 (HY-15648) is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A.

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GSK-J2 sodium Chemical Structure

CAS No. : 2108665-15-0

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Other In-stock Forms of GSK-J2 sodium:

GSK-J2

Other Forms of GSK-J2 sodium:

GSK-J2 In-stock

2 Publications Citing Use of MCE GSK-J2 sodium

IHC

: GSK-J2 sodium purchased from MedChemExpress. Usage Cited in: Front Mol Neurosci. 2017 Mar 13;10:51. [Abstract]; GSK-J1 impaired zebrafish hair cell regeneration. 5 dpf larvae are treated with 400 μM Neomycin for 1 h followed by GSK-J1 exposure for 24 in the presence of BrdU. GSK-J1 significantly reduces the numbers of myosinVI-positive (green) hair cells and BrdU-positive (red) replicating cells.

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Description	GSK-J2 sodium is the sodium form of GSK-J2 (HY-15648A). GSK-J2 is an isomer of GSK-J1, and does not have any specific activity. GSK-J1 (HY-15648) is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A^[1].
Molecular Weight	411.43
Formula	C₂₂H₂₂N₅NaO₂
CAS No.	2108665-15-0
SMILES	O=C(CCNC1=CC(N2CCC3=C(CC2)C=CC=C3)=NC(C4=CN=CC=C4)=N1)O[Na]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (268 KB) Handling Instructions (2659 KB)
References	[1]. Heinemann B, et al. Inhibition of demethylases by GSK-J1/J4. Nature. 2014 Oct 2;514(7520):E1-2 [Content Brief]

GSK-J2 sodium Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GSK-J22108665-15-0OthersInactiveIsomerGSK-J1Inhibitorinhibitorinhibit

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GSK-J2 sodium

Other Forms of GSK-J2 sodium:

GSK-J2 sodium Related Antibodies

2 Publications Citing Use of MCE GSK-J2 sodium

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Biological Activity

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