2. Others Immunology/Inflammation NF-κB
  3. Isotope-Labeled Compounds COX NF-κB
  4. Guaiacol-d3

Guaiacol-d3  (Synonyms: 2-Methoxyphenol-d3)

Cat. No.: HY-N1380S1 Purity: ≥99.0%
COA Handling Instructions

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Guaiacol-d3 is the deuterium labeled Guaiacol. Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation. Guaiacol has an anti-inflammatory activity[1].

For research use only. We do not sell to patients.

Guaiacol-d<sub>3</sub> Chemical Structure

Guaiacol-d3 Chemical Structure

CAS No. : 74495-69-5

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10 mg USD 40 In-stock
25 mg USD 75 In-stock
50 mg USD 125 In-stock
100 mg USD 200 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Guaiacol-d3:

Guaiacol-d3 Related Antibodies

Top Publications Citing Use of Products

View All COX Isoform Specific Products:

View All Isoforms
COX COX-1 COX-2 COX-3

View All NF-κB Isoform Specific Products:

View All Isoforms
NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

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  • Customer Review

Description

Guaiacol-d3 is the deuterium labeled Guaiacol. Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation. Guaiacol has an anti-inflammatory activity[1].

Molecular Weight

127.16

Formula

C7H5D3O2
CAS No.
Unlabeled CAS

90-05-1
Appearance

Liquid (Density: 1.137 g/cm3)

Color

Light yellow to light brown

SMILES

OC1=CC=CC=C1OC([2H])([2H])[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (786.41 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.8641 mL 39.3205 mL 78.6411 mL
5 mM 1.5728 mL 7.8641 mL 15.7282 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (252 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 7.8641 mL 39.3205 mL 78.6411 mL 196.6027 mL
5 mM 1.5728 mL 7.8641 mL 15.7282 mL 39.3205 mL
10 mM 0.7864 mL 3.9321 mL 7.8641 mL 19.6603 mL
15 mM 0.5243 mL 2.6214 mL 5.2427 mL 13.1068 mL
20 mM 0.3932 mL 1.9660 mL 3.9321 mL 9.8301 mL
25 mM 0.3146 mL 1.5728 mL 3.1456 mL 7.8641 mL
30 mM 0.2621 mL 1.3107 mL 2.6214 mL 6.5534 mL
40 mM 0.1966 mL 0.9830 mL 1.9660 mL 4.9151 mL
50 mM 0.1573 mL 0.7864 mL 1.5728 mL 3.9321 mL
60 mM 0.1311 mL 0.6553 mL 1.3107 mL 3.2767 mL
80 mM 0.0983 mL 0.4915 mL 0.9830 mL 2.4575 mL
100 mM 0.0786 mL 0.3932 mL 0.7864 mL 1.9660 mL
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Guaiacol-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Guaiacol-d374495-69-52-Methoxyphenol-d3Isotope-Labeled CompoundsCOXNF-κBCyclooxygenaseNuclear factor-κBNuclear factor-kappaBInhibitorinhibitorinhibit

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