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  3. Isotope-Labeled Compounds
  4. Guaifenesin-d3

Guaifenesin-d3  (Synonyms: Guaiacol glyceryl ether-d3; Guaiphenesin-d3; Glycerol guaiacolate-d3)

Cat. No.: HY-B0264S Purity: 99.00%
SDS COA Handling Instructions

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Guaifenesin-d3 is the deuterium labeled Guaifenesin. Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough[1][2].

For research use only. We do not sell to patients.

Guaifenesin-d<sub>3</sub> Chemical Structure

Guaifenesin-d3 Chemical Structure

CAS No. : 1189924-85-3

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1 mg USD 140 In-stock
5 mg USD 350 In-stock
10 mg USD 560 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Guaifenesin-d3:

Guaifenesin-d3 Related Antibodies

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  • Biological Activity

  • Purity & Documentation

  • References

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Description

Guaifenesin-d3 is the deuterium labeled Guaifenesin. Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Guaifenesin-d3 Related Antibodies
Molecular Weight

201.23

Formula

C10H11D3O4
CAS No.
Unlabeled CAS

93-14-1
Appearance

Solid

Color

White to off-white

SMILES

OCC(O)COC1=C(C=CC=C1)OC([2H])([2H])[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 30 mg/mL (149.08 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : ≥ 30 mg/mL (149.08 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMF : ≥ 30 mg/mL (149.08 mM)

DMF : ≥ 30 mg/mL (149.08 mM)

Ethanol : ≥ 15 mg/mL (74.54 mM)

Ethanol : ≥ 15 mg/mL (74.54 mM)

PBS (pH 7.2) : ≥ 5 mg/mL (24.85 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.9694 mL 24.8472 mL 49.6944 mL
5 mM 0.9939 mL 4.9694 mL 9.9389 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
PBS (pH 7.2) / Ethanol / Ethanol / DMSO / DMSO / DMF / DMF 1 mM 4.9694 mL 24.8472 mL 49.6944 mL 124.2360 mL
5 mM 0.9939 mL 4.9694 mL 9.9389 mL 24.8472 mL
10 mM 0.4969 mL 2.4847 mL 4.9694 mL 12.4236 mL
15 mM 0.3313 mL 1.6565 mL 3.3130 mL 8.2824 mL
20 mM 0.2485 mL 1.2424 mL 2.4847 mL 6.2118 mL
Ethanol / Ethanol / DMSO / DMSO / DMF / DMF 25 mM 0.1988 mL 0.9939 mL 1.9878 mL 4.9694 mL
30 mM 0.1656 mL 0.8282 mL 1.6565 mL 4.1412 mL
40 mM 0.1242 mL 0.6212 mL 1.2424 mL 3.1059 mL
50 mM 0.0994 mL 0.4969 mL 0.9939 mL 2.4847 mL
60 mM 0.0828 mL 0.4141 mL 0.8282 mL 2.0706 mL
DMSO / DMSO / DMF / DMF 80 mM 0.0621 mL 0.3106 mL 0.6212 mL 1.5529 mL
100 mM 0.0497 mL 0.2485 mL 0.4969 mL 1.2424 mL
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Guaifenesin-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Guaifenesin-d31189924-85-3Guaiacol glyceryl ether-d3Guaiphenesin-d3Glycerol guaiacolate-d3Isotope-Labeled CompoundsInhibitorinhibitorinhibit

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