Guanosine 5'-triphosphate, ammonium salt-¹⁵N₅ 

Guanosine 5'-triphosphate, ammonium salt-¹⁵N₅ is the ¹⁵N labeled Guanosine 5'-triphosphate, ammonium salt[1].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

596.27

C₁₀H₂₈N₄¹⁵N₅O₁₄P₃

O[C@H]1[C@@H](COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)O[C@@H]([15N]2C([15N]=C([15NH2])[15NH]C3=O)=C3[15N]=C2)[C@H]1O.[NH4+].[NH4+].[NH4+].[NH4+]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]