1. Others Metabolic Enzyme/Protease Anti-infection Cell Cycle/DNA Damage
  2. Isotope-Labeled Compounds Endogenous Metabolite SARS-CoV Nucleoside Antimetabolite/Analog DNA/RNA Synthesis
  3. Guanosine triphosphate-15N5,d14 dilithium

Guanosine triphosphate-15N5,d14 dilithium  (Synonyms: GTP-15N5,d14 dilithium)

Cat. No.: HY-113225S4
Handling Instructions

Guanosine triphosphate-15N5,d14 (GTP-15N5,d14) dilithium is deuterium and 15N labeled Guanosine triphosphate (HY-113225). Guanosine triphosphate is a native nucleotide. The derivatives of GTP may be used as specific inhibitors against COVID-19.

For research use only. We do not sell to patients.

Guanosine triphosphate-<sup>15</sup>N<sub>5</sub>,d<sub>14</sub> dilithium Chemical Structure

Guanosine triphosphate-15N5,d14 dilithium Chemical Structure

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Description

Guanosine triphosphate-15N5,d14 (GTP-15N5,d14) dilithium is deuterium and 15N labeled Guanosine triphosphate (HY-113225). Guanosine triphosphate is a native nucleotide. The derivatives of GTP may be used as specific inhibitors against COVID-19.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

554.10

Formula

C10D14Li215N5O14P3

Unlabeled CAS

86-01-1

SMILES

O=P(O[2H])(O[Li])OP(OP(OC([2H])([2H])[C@@]1([2H])O[C@]([15N]2C([15N]=C([15N]([2H])[2H])[15N]([2H])C3=O)=C3[15N]=C2[2H])([2H])[C@](O[2H])([2H])[C@]1([2H])O[2H])(O[2H])=O)(O[Li])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Guanosine triphosphate-15N5,d14 dilithium
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HY-113225S4
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