Guanylin(human) TFA

Cat. No.: HY-P1179A Purity: 96.64%: FAQs
Data Sheet SDS COA Handling Instructions

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Guanylin(human) TFA, a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin(human) TFA is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Guanylin(human) TFA Chemical Structure

Size	Price	Stock	Quantity
1 mg	USD 350	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 950	Get quote	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Guanylin(human) TFA:

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Purity & Documentation
References
Customer Review

Description

Molecular Weight

1572.68

Formula

C₆₀H₈₈F₃N₁₅O₂₃S₄

Appearance

Solid

Color

White to off-white

Sequence Shortening

PGTCEICAYAACTGC (Disulfide bridge:Cys4-Cys12;Cys7-Cys15)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (63.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.6359 mL	3.1793 mL	6.3586 mL
5 mM	0.1272 mL	0.6359 mL	1.2717 mL
10 mM	0.0636 mL	0.3179 mL	0.6359 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 96.64%

Select Batch:

Data Sheet (267 KB) SDS (252 KB)

COA (242 KB) RP-HPLC (113 KB) MS (225 KB)

Handling Instructions (2659 KB)

References

[1]. M G Currie, et al. Guanylin: an endogenous activator of intestinal guanylate cyclase. Proc Natl Acad Sci U S A. 1992 Feb 1;89(3):947-51. [Content Brief]

[2]. J Bełtowski. Guanylin and related peptides. J Physiol Pharmacol. 2001 Sep;52(3):351-75. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	0.6359 mL	3.1793 mL	6.3586 mL	15.8964 mL
	5 mM	0.1272 mL	0.6359 mL	1.2717 mL	3.1793 mL
	10 mM	0.0636 mL	0.3179 mL	0.6359 mL	1.5896 mL
	15 mM	0.0424 mL	0.2120 mL	0.4239 mL	1.0598 mL
	20 mM	0.0318 mL	0.1590 mL	0.3179 mL	0.7948 mL
	25 mM	0.0254 mL	0.1272 mL	0.2543 mL	0.6359 mL
	30 mM	0.0212 mL	0.1060 mL	0.2120 mL	0.5299 mL
	40 mM	0.0159 mL	0.0795 mL	0.1590 mL	0.3974 mL
	50 mM	0.0127 mL	0.0636 mL	0.1272 mL	0.3179 mL
	60 mM	0.0106 mL	0.0530 mL	0.1060 mL	0.2649 mL