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  3. Gymnemagenin

Gymnemagenin is a triterpenoid isolated from G. sylvestre. Gymnemagenin is an agent for diabetes and obesity and also possesses antiviral properties.

For research use only. We do not sell to patients.

Gymnemagenin Chemical Structure

Gymnemagenin Chemical Structure

CAS No. : 22467-07-8

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1 mg USD 125 In-stock
5 mg USD 400 In-stock
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Description

Gymnemagenin is a triterpenoid isolated from G. sylvestre. Gymnemagenin is an agent for diabetes and obesity and also possesses antiviral properties[1][2].

In Vivo

Gymnemagenin has a poor oral bioavailability (~ 14 %) in rats[2].
Gymnemagenin has a short half-life and a high clearance in rats[2].
Gymnemagenin metabolizes rapidly with a short apparent and intrinsic half-life (~ 7 min) and high intrinsic clearance[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

506.71

Formula

C30H50O6

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC[C@]1([C@H]2O)[C@](CC(C)(C)[C@H]2O)([H])C3=CC[C@@]4([H])[C@@](C)(CC[C@]5([H])[C@@]4(CC[C@H](O)[C@@]5(C)CO)C)[C@]3(C)C[C@@H]1O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 30 mg/mL (59.21 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9735 mL 9.8676 mL 19.7352 mL
5 mM 0.3947 mL 1.9735 mL 3.9470 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9735 mL 9.8676 mL 19.7352 mL 49.3379 mL
5 mM 0.3947 mL 1.9735 mL 3.9470 mL 9.8676 mL
10 mM 0.1974 mL 0.9868 mL 1.9735 mL 4.9338 mL
15 mM 0.1316 mL 0.6578 mL 1.3157 mL 3.2892 mL
20 mM 0.0987 mL 0.4934 mL 0.9868 mL 2.4669 mL
25 mM 0.0789 mL 0.3947 mL 0.7894 mL 1.9735 mL
30 mM 0.0658 mL 0.3289 mL 0.6578 mL 1.6446 mL
40 mM 0.0493 mL 0.2467 mL 0.4934 mL 1.2334 mL
50 mM 0.0395 mL 0.1974 mL 0.3947 mL 0.9868 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Gymnemagenin
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HY-N2268
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