H2TMpyP-2 chloride  (Synonyms: Tetrakis(2-N-methylpyridyl)porphine chloride)

H2TMpyP-2 (tetrakis(2-N-methylpyridyl)porphine) chloride is an active photosensitizer with strong absorption properties in the visible to near-infrared region and excellent singlet oxygen quantum yield. Captisol-TMPyP complexes can be used in supramolecular nanosynthesis to increase singlet oxygen production, improve photostability and better photosensitization, and support photodynamic therapy activity. The Captisol:TMPyP complex also exhibited antibacterial activity against Escherichia coli and was cytotoxic against lung cancer A549 cells^[1].

820.64

C₄₄H₃₈Cl₄N₈

129051-18-9

Solid

Brown to black

C[N+]1=CC=CC=C1C2=C3C=CC(C(C4=CC=CC=[N+]4C)=C5C=CC(N5)=C(C6=CC=CC=[N+]6C)C(C=C7)=NC7=C(C8=CC=CC=[N+]8C)C9=CC=C2N9)=N3.[Cl-].[Cl-].[Cl-].[Cl-]

Room temperature in continental US; may vary elsewhere.

4°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

• [1]. Khurana R, et al. Supramolecular Nanorods of (N-Methylpyridyl) Porphyrin With Captisol: Effective Photosensitizer for Anti-bacterial and Anti-tumor Activities. Front Chem. 2019 Jun 21;7:452.  [Content Brief]