2. Epigenetics
  3. Histone Demethylase
  4. H3K4(Me) (1-20)

H3K4(Me) (1-20), a histone peptide. H3K4me is an intricately regulated posttranslational modification, which is broadly associated with enhancers and promoters of actively transcribed genomic loci.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

H3K4(Me) (1-20) Chemical Structure

H3K4(Me) (1-20) Chemical Structure

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Based on 1 publication(s) in Google Scholar

H3K4(Me) (1-20) Related Antibodies

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Description

H3K4(Me) (1-20), a histone peptide. H3K4me is an intricately regulated posttranslational modification, which is broadly associated with enhancers and promoters of actively transcribed genomic loci[1].

Molecular Weight

2197.58

Formula

C92H169N35O27
Appearance

Solid

Color

White to off-white

Sequence

Ala-Arg-Thr-{Lys(Me)}-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu
Sequence Shortening

ART-{Lys(Me)}-QTARKSTGGKAPRKQL
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (22.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4550 mL 2.2752 mL 4.5505 mL
5 mM 0.0910 mL 0.4550 mL 0.9101 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.82%

SDS (252 KB)

COA (250 KB) RP-HPLC (88 KB) MS (270 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.4550 mL 2.2752 mL 4.5505 mL 11.3761 mL
5 mM 0.0910 mL 0.4550 mL 0.9101 mL 2.2752 mL
10 mM 0.0455 mL 0.2275 mL 0.4550 mL 1.1376 mL
15 mM 0.0303 mL 0.1517 mL 0.3034 mL 0.7584 mL
20 mM 0.0228 mL 0.1138 mL 0.2275 mL 0.5688 mL
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H3K4(Me) (1-20) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

H3K4(Me) (1-20)Histone DemethylasemethylationcomplexhistonesubstrateInhibitorinhibitorinhibit

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