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  3. Biochemical Assay Reagents
  4. HATU

HATU (1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate) is a reagent used in peptide coupling chemistry to generate an active ester from a carboxylic acid. HATU can be used along with Hünig's base (N,N-diisopropylethylamine, DIPEA) to form amide bonds.

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HATU Chemical Structure

HATU Chemical Structure

CAS No. : 148893-10-1

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HATU Related Antibodies

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Description

HATU (1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate) is a reagent used in peptide coupling chemistry to generate an active ester from a carboxylic acid. HATU can be used along with Hünig's base (N,N-diisopropylethylamine, DIPEA) to form amide bonds[1].

Molecular Weight

380.23

Formula

C10H15F6N6OP
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

F[P-](F)(F)(F)(F)F.C/[N+](C)=C(N(C)C)/ON1C2=NC=CC=C2N=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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HATU Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HATU148893-10-1Biochemical Assay Reagentspeptide couplingactive esterHünig's baseamide bondInhibitorinhibitorinhibit

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