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  4. HBpep-SA acetate

HBpep-SA acetate is a cell membrane-permeable peptide condensate that phase separates to form stable droplets at pH values below 6.5. HBpep-SA acetate is able to directly and efficiently deliver a variety of macromolecules, ranging from therapeutic peptides as small as 726 Da to large enzymes as large as 430 kDa, and the loaded condensates remain stable under near-physiological and serum conditions until internalized by cells. HBpep-SA acetate can be used for intracellular delivery of large numbers of macromolecules and as a vector for mRNA-based vaccines.

For research use only. We do not sell to patients.

HBpep-SA acetate Chemical Structure

HBpep-SA acetate Chemical Structure

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1 mg USD 235 In-stock
5 mg USD 580 In-stock
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Based on 1 publication(s) in Google Scholar

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HBpep-SA acetate Related Antibodies

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Description

HBpep-SA acetate is a cell membrane-permeable peptide condensate that phase separates to form stable droplets at pH values below 6.5. HBpep-SA acetate is able to directly and efficiently deliver a variety of macromolecules, ranging from therapeutic peptides as small as 726 Da to large enzymes as large as 430 kDa, and the loaded condensates remain stable under near-physiological and serum conditions until internalized by cells. HBpep-SA acetate can be used for intracellular delivery of large numbers of macromolecules and as a vector for mRNA-based vaccines[1].

Molecular Weight

3132.41 (free base)

Formula

C145H187N39O37S2.xC2H4O2
Appearance

Solid

Color

White to off-white

Sequence

Gly-His-Gly-Val-Tyr-Gly-His-Gly-Val-Tyr-Gly-His-Gly-Pro-Tyr-{Lys(NHS-SS-Ac)}-Gly-His-Gly-Pro-Tyr-Gly-His-Gly-Leu-Tyr-Trp
Sequence Shortening

GHGVYGHGVYGHGPY-{Lys(NHS-SS-Ac)}-GHGPYGHGLYW
SMILES

O=C(NCCCC[C@@H](C(NCC(N[C@@H](CC1=CNC=N1)C(NCC(N2[C@@H](CCC2)C(N[C@@H](CC3=CC=C(C=C3)O)C(NCC(N[C@@H](CC4=CNC=N4)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CC6=CNC7=CC=CC=C67)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC([C@H](CC8=CC=C(C=C8)O)NC([C@H]9N(C(CNC([C@H](CC%10=CNC=N%10)NC(CNC([C@H](CC%11=CC=C(C=C%11)O)NC([C@H](C(C)C)NC(CNC([C@H](CC%12=CNC=N%12)NC(CNC([C@H](CC%13=CC=C(C=C%13)O)NC([C@H](C(C)C)NC(CNC([C@H](CC%14=CNC=N%14)NC(CN)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC9)=O)=O)OCCSSCCOC(C)=O.OC(C)=O.[x]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL

*"≥" means soluble, but saturation unknown.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References
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HBpep-SA acetate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HBpep-SAOthersmRNApeptidedropletdeliveryInhibitorinhibitorinhibit

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