2. Metabolic Enzyme/Protease
  3. Carbonic Anhydrase
  4. hCAIX-IN-21

hCAIX-IN-21 (compound 16c) is a potent hCAIX inhibitor with KI values of 5.2, 3.5, 12.6, 13600 nM for hCAIX, hCA II, hCA XII, hCA I, respectively. hCAIX-IN-21 inhibits cathepsin B enzyme activity.

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hCAIX-IN-21 Chemical Structure

hCAIX-IN-21 Chemical Structure

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hCAIX-IN-21 Related Antibodies

Top Publications Citing Use of Products

View All Carbonic Anhydrase Isoform Specific Products:

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CA CA I CA Ⅱ CA Ⅸ CA XII

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Description

hCAIX-IN-21 (compound 16c) is a potent hCAIX inhibitor with KI values of 5.2, 3.5, 12.6, 13600 nM for hCAIX, hCA II, hCA XII, hCA I, respectively. hCAIX-IN-21 inhibits cathepsin B enzyme activity[1].

IC50 & Target[1]

hCA IX

5.2 nM (Ki)

hCA II

3.5 nM (Ki)

hCA XII

12.6 nM (Ki)

hCA I

13600 nM (Ki)

Molecular Weight

456.45

Formula

C20H17FN6O4S
SMILES

O=C(C1=NN(C2=CC=C(S(=O)(N)=O)C=C2)C(C3=C(C)N(C4=CC=C(F)C=C4)N=N3)=C1)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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hCAIX-IN-21 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

hCAIX-IN-21Carbonic AnhydraseCarbonate dehydratasecathepsin BcancerInhibitorinhibitorinhibit

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hCAIX-IN-21
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HY-159128
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