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  5. Head activator neuropeptide

Head activator neuropeptide is a mitogen for mammalian cell lines of neuronal or neuroendocrine origin. Head activator neuropeptide signals by binding GPR37 and stimulates cells to enter mitosis.

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Head activator neuropeptide Chemical Structure

Head activator neuropeptide Chemical Structure

CAS No. : 79943-68-3

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Head activator neuropeptide Related Antibodies

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Description

Head activator neuropeptide is a mitogen for mammalian cell lines of neuronal or neuroendocrine origin. Head activator neuropeptide signals by binding GPR37 and stimulates cells to enter mitosis[1].

IC50 & Target

GPR37[1]
In Vitro

Head activator neuropeptide (2 nM, 0-60 min) stimulates internalisation of GPR37 in COS-7 cell transfected with GPR37-FLAG[1].
Head activator neuropeptide (EC50: 3.3 nM) increases in Ca2+ mobilisation in CHO-K1 cells transfected with apoaequorin and GPR37[1].
Head activator neuropeptide (EC50: 5.6 nM) stimulates a current increase in frog oocytes expressing GPR37[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Head activator neuropeptide Related Antibodies
Molecular Weight

1125.32

Formula

C54H84N12O14
CAS No.
Sequence Shortening

Glp-PPGGSKVILF
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Head activator neuropeptide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Head activator neuropeptide79943-68-3OthersCOS-7CHO-K1mitogenmitosisneuropeptideInhibitorinhibitorinhibit

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Head activator neuropeptide
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