Heart-homing peptide TFA

Cat. No.: HY-P10641A: FAQs
Data Sheet Handling Instructions Technical Support

Heart-homing peptide TFA is a Pentapeptide, CRPPR. CRPPR is a linear peptide containing arginine that has been identified as a heart-homing peptide owing to its ability to specifically bind to heart endothelium, and cysteine-rich protein-2 (CRIP-2) has been proposed as the receptor. Heart-homing peptide TFA can be used for conjugating liposomes.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Heart-homing peptide TFA Chemical Structure

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Other Forms of Heart-homing peptide TFA:

Heart-homing peptide Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

741.78

Formula

C₂₇H₄₆F₃N₁₁O₈S

Appearance

Solid

Sequence

Cys-Arg-Pro-Pro-Arg

Sequence Shortening

CRPPR

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (134.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.3481 mL	6.7405 mL	13.4811 mL
5 mM	0.2696 mL	1.3481 mL	2.6962 mL
10 mM	0.1348 mL	0.6741 mL	1.3481 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

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In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zhang H, et al. The cargo of CRPPR-conjugated liposomes crosses the intact murine cardiac endothelium. J Control Release. 2012 Oct 10;163(1):10-7. [Content Brief]

[2]. Rodríguez-Castejón J, et al. Targeting strategies with lipid vectors for nucleic acid supplementation therapy in Fabry disease: a systematic review. Drug Deliv Transl Res. 2024 Apr 8. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.3481 mL	6.7405 mL	13.4811 mL	33.7027 mL
	5 mM	0.2696 mL	1.3481 mL	2.6962 mL	6.7405 mL
	10 mM	0.1348 mL	0.6741 mL	1.3481 mL	3.3703 mL
	15 mM	0.0899 mL	0.4494 mL	0.8987 mL	2.2468 mL
	20 mM	0.0674 mL	0.3370 mL	0.6741 mL	1.6851 mL
	25 mM	0.0539 mL	0.2696 mL	0.5392 mL	1.3481 mL
	30 mM	0.0449 mL	0.2247 mL	0.4494 mL	1.1234 mL
	40 mM	0.0337 mL	0.1685 mL	0.3370 mL	0.8426 mL
	50 mM	0.0270 mL	0.1348 mL	0.2696 mL	0.6741 mL
	60 mM	0.0225 mL	0.1123 mL	0.2247 mL	0.5617 mL
	80 mM	0.0169 mL	0.0843 mL	0.1685 mL	0.4213 mL
	100 mM	0.0135 mL	0.0674 mL	0.1348 mL	0.3370 mL