2. PROTAC
  3. PROTAC Linkers
  4. Heptaethylene glycol

Heptaethylene glycol  (Synonyms: HO-PEG7-OH)

Cat. No.: HY-141231 Purity: ≥97.0%
SDS COA Handling Instructions

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Heptaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Heptaethylene glycol Chemical Structure

Heptaethylene glycol Chemical Structure

CAS No. : 5617-32-3

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Based on 1 publication(s) in Google Scholar

Heptaethylene glycol Related Antibodies

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Description

Heptaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Heptaethylene glycol Related Antibodies
Molecular Weight

326.38

Formula

C14H30O8
CAS No.
Appearance

<17.8°C Solid,>18.8°C Liquid

Color

Colorless to off-white

SMILES

OCCOCCOCCOCCOCCOCCOCCO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥97.0%

SDS (393 KB)

COA (238 KB) HNMR (122 KB)

Handling Instructions (2659 KB)
References
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Heptaethylene glycol Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Heptaethylene glycol5617-32-3HO-PEG7-OHPROTAC LinkersInhibitorinhibitorinhibit

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