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Herbimycin C  (Synonyms: Antibiotic TAN 420D)

Cat. No.: HY-126699
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Herbimycin C is a bacterial metabolite originally isolated from S. hygroscopicus. It is cytotoxic to HeLa and Ehrlich cells (IC50s=7.3 and 1.2 μg/mL, respectively).

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Herbimycin C Chemical Structure

Herbimycin C Chemical Structure

CAS No. : 91700-92-4

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Herbimycin C Related Antibodies

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Description

Herbimycin C is a bacterial metabolite originally isolated from S. hygroscopicus. It is cytotoxic to HeLa and Ehrlich cells (IC50s=7.3 and 1.2 μg/mL, respectively).

Cellular Effect
Cell Line Type Value Description References
A2780 IC50
3.01 μM
Compound: 2
Antiproliferative activity against human A2780 assessed as reduction in cell viability measured after 96 hrs by MTT assay
Antiproliferative activity against human A2780 assessed as reduction in cell viability measured after 96 hrs by MTT assay
[PMID: 27476419]
A-375 IC50
2.43 μM
Compound: 2
Antiproliferative activity against human A375 assessed as reduction in cell viability measured after 96 hrs by MTT assay
Antiproliferative activity against human A375 assessed as reduction in cell viability measured after 96 hrs by MTT assay
[PMID: 27476419]
BGC-823 IC50
3.99 μM
Compound: 2
Antiproliferative activity against human BGC823 assessed as reduction in cell viability measured after 96 hrs by MTT assay
Antiproliferative activity against human BGC823 assessed as reduction in cell viability measured after 96 hrs by MTT assay
[PMID: 27476419]
HCT-116 IC50
9.39 μM
Compound: 2
Antiproliferative activity against human HCT116 assessed as reduction in cell viability measured after 96 hrs by MTT assay
Antiproliferative activity against human HCT116 assessed as reduction in cell viability measured after 96 hrs by MTT assay
[PMID: 27476419]
MCF7 IC50
5.07 μM
Compound: 2
Antiproliferative activity against human MCF7 assessed as reduction in cell viability measured after 96 hrs by MTT assay
Antiproliferative activity against human MCF7 assessed as reduction in cell viability measured after 96 hrs by MTT assay
[PMID: 27476419]
SW1990 IC50
8.62 μM
Compound: 2
Antiproliferative activity against human SW1990 assessed as reduction in cell viability measured after 96 hrs by MTT assay
Antiproliferative activity against human SW1990 assessed as reduction in cell viability measured after 96 hrs by MTT assay
[PMID: 27476419]
Molecular Weight

560.64

Formula

C29H40N2O9
CAS No.
SMILES

CO[C@@]1([H])C(C(C(NC(/C(C)=C/C=C/[C@H](OC)[C@@H](OC(N)=O)/C(C)=C/[C@H](C)[C@@H](O)[C@@H](OC)C[C@@H]1C)=O)=C2)=O)=CC2=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Herbimycin C Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Herbimycin C91700-92-4Antibiotic TAN 420DOthersInhibitorinhibitorinhibit

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