2. Immunology/Inflammation
  3. Thrombopoietin Receptor
  4. Rafutrombopag (tautomerism)

Rafutrombopag (tautomerism)  (Synonyms: Hetrombopag (tautomerism); SHR-8735 (tautomerism))

Cat. No.: HY-122620 Purity: 98.16%
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Rafutrombopag (tautomerism) is a potent thrombopoietin receptor agonist. Rafutrombopag (tautomerism) is efficacious and well tolerated with a manageable safety profile. Rafutrombopag (tautomerism) has the potential for the research of immune thrombocytopenia.

For research use only. We do not sell to patients.

Rafutrombopag (tautomerism) Chemical Structure

Rafutrombopag (tautomerism) Chemical Structure

CAS No. : 2114365-78-3

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1 mg USD 260 In-stock
5 mg USD 650 In-stock
10 mg USD 1050 In-stock
25 mg USD 2150 In-stock
50 mg USD 3450 In-stock
100 mg USD 5400 Get quote
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Based on 1 publication(s) in Google Scholar

Other Forms of Rafutrombopag (tautomerism):

Rafutrombopag (tautomerism) Related Antibodies

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Description

Rafutrombopag (tautomerism) is a potent thrombopoietin receptor agonist. Rafutrombopag (tautomerism) is efficacious and well tolerated with a manageable safety profile. Rafutrombopag (tautomerism) has the potential for the research of immune thrombocytopenia[1].

Clinical Trial
Molecular Weight

458.47

Formula

C25H22N4O5
CAS No.
Appearance

Solid

Color

Brown to dark brown

SMILES

O=C(C1=CC=C(C2=C(O)C(/N=N/C3C(N(C4=CC=C5C(CCCC5)=C4)N=C3C)=O)=CC=C2)O1)O
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMF : 6.25 mg/mL (13.63 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1812 mL 10.9058 mL 21.8117 mL
5 mM 0.4362 mL 2.1812 mL 4.3623 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMF 1 mM 2.1812 mL 10.9058 mL 21.8117 mL 54.5292 mL
5 mM 0.4362 mL 2.1812 mL 4.3623 mL 10.9058 mL
10 mM 0.2181 mL 1.0906 mL 2.1812 mL 5.4529 mL
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Rafutrombopag (tautomerism) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rafutrombopag (tautomerism)2114365-78-3Hetrombopag (tautomerism) SHR-8735 (tautomerism)Thrombopoietin Receptorthrombopoietin receptorefficaciousimmune thrombocytopeniasafetyInhibitorinhibitorinhibit

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