2. Peptides
  3. Peptide and Derivatives
  4. Inhibitors and Substrates
  5. Hirugen

Hirugen is a derivative of hirudin, an anticoagulant protein found in leeches.

For research use only. We do not sell to patients.

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Hirugen Chemical Structure

Hirugen Chemical Structure

CAS No. : 121822-23-9

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5 mg USD 410 In-stock
10 mg USD 580 In-stock
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Based on 1 publication(s) in Google Scholar

Hirugen Related Antibodies

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Description

Hirugen is a derivative of hirudin, an anticoagulant protein found in leeches[1].

Molecular Weight

1534.55

Formula

C65H91N13O28S
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-{SO3H-Tyr}-Leu
Sequence Shortening

NGDFEEIPEE-{SO3H-Tyr}-L
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (65.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6517 mL 3.2583 mL 6.5166 mL
5 mM 0.1303 mL 0.6517 mL 1.3033 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.6517 mL 3.2583 mL 6.5166 mL 16.2914 mL
5 mM 0.1303 mL 0.6517 mL 1.3033 mL 3.2583 mL
10 mM 0.0652 mL 0.3258 mL 0.6517 mL 1.6291 mL
15 mM 0.0434 mL 0.2172 mL 0.4344 mL 1.0861 mL
20 mM 0.0326 mL 0.1629 mL 0.3258 mL 0.8146 mL
25 mM 0.0261 mL 0.1303 mL 0.2607 mL 0.6517 mL
30 mM 0.0217 mL 0.1086 mL 0.2172 mL 0.5430 mL
40 mM 0.0163 mL 0.0815 mL 0.1629 mL 0.4073 mL
50 mM 0.0130 mL 0.0652 mL 0.1303 mL 0.3258 mL
60 mM 0.0109 mL 0.0543 mL 0.1086 mL 0.2715 mL
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Hirugen Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hirugen121822-23-9Othersanticoagulant proteinhirudinInhibitorinhibitorinhibit

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