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  3. HIV-1 inhibitor-33

HIV-1 inhibitor-33 (compound 5n) is a potent and selective HIV-1 inhibitor with an EC50 of 8.6 nM for HIV-1 and a CC50 of 18 μM in MT-4 cells. HIV-1 inhibitor-33 can be used for researching AIDS.

For research use only. We do not sell to patients.

HIV-1 inhibitor-33 Chemical Structure

HIV-1 inhibitor-33 Chemical Structure

CAS No. : 2395777-43-0

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Description

HIV-1 inhibitor-33 (compound 5n) is a potent and selective HIV-1 inhibitor with an EC50 of 8.6 nM for HIV-1 and a CC50 of 18 μM in MT-4 cells. HIV-1 inhibitor-33 can be used for researching AIDS[1].

IC50 & Target[1]

HIV-1 (WT)

8.6 nM (EC50)

Cellular Effect
Cell Line Type Value Description References
MT4 CC50
18 μM
Compound: 5n
Cytotoxicity against human MT4 cells assessed as inhibition of cell viability by measuring reduction in absorbance at OD540 by MTT assay
Cytotoxicity against human MT4 cells assessed as inhibition of cell viability by measuring reduction in absorbance at OD540 by MTT assay
[PMID: 31767136]
Molecular Weight

428.53

Formula

C25H28N6O

CAS No.
SMILES

CC(C=CC=C1C)=C1OC2=CC=NC(NC3CCN(CC3)CC4=NNC5=C4C=CC=C5)=N2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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HIV-1 inhibitor-33 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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HIV-1 inhibitor-33
Cat. No.:
HY-146090
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