2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. HSP
  4. HM03 trihydrochloride

HM03 trihydrochloride is a potent and selective HSPA5 (Heat shock 70kDa protein 5, also known as Bip, Grp78) inhibitor. HM03 trihydrochloride has anticancer activity.

For research use only. We do not sell to patients.

HM03 trihydrochloride Chemical Structure

HM03 trihydrochloride Chemical Structure

CAS No. : 1082532-95-3

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HM03 trihydrochloride Related Antibodies

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Description

HM03 trihydrochloride is a potent and selective HSPA5 (Heat shock 70kDa protein 5, also known as Bip, Grp78) inhibitor. HM03 trihydrochloride has anticancer activity[1].

In Vitro

HM03 trihydrochloride (0.1-50 μM; 72 hours) exhibits over 50% inhibition at 25 µM concentration in HCT116 cells[1].
HM03 trihydrochloride forms more binding interactions with HSPA5 and HSPA9 than with the other HSP70 proteins[1].
HM03 trihydrochloride exhibits promising inhibition activities from cancer cell viability and tumor inhibition assays[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

HM03 trihydrochloride Related Antibodies
Molecular Weight

572.35

Formula

C26H30Cl4N4O2
CAS No.
SMILES

OC1=CC=C(NC2=C(C=C(OC)C=C3)C3=NC4=CC(Cl)=CC=C42)C=C1CN5CCN(C)CC5.[H]Cl.[H]Cl.[H]Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HM03 trihydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HM03 trihydrochloride1082532-95-3HSPHeat shock proteinsheatshockproteincancercellHCT116tumorInhibitorinhibitorinhibit

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HM03 trihydrochloride
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HY-125974A
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