2. PROTAC
  3. PROTAC Linkers
  4. HO-PEG24-OH

HO-PEG24-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

HO-PEG24-OH Chemical Structure

HO-PEG24-OH Chemical Structure

CAS No. : 2243942-52-9

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50 mg USD 95 In-stock
100 mg USD 155 In-stock
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Based on 1 publication(s) in Google Scholar

HO-PEG24-OH Related Antibodies

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PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

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Description

HO-PEG24-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

Molecular Weight

1075.28

Formula

C48H98O25
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (46.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9300 mL 4.6500 mL 9.2999 mL
5 mM 0.1860 mL 0.9300 mL 1.8600 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (247 KB) HNMR (297 KB) MS (176 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.9300 mL 4.6500 mL 9.2999 mL 23.2498 mL
5 mM 0.1860 mL 0.9300 mL 1.8600 mL 4.6500 mL
10 mM 0.0930 mL 0.4650 mL 0.9300 mL 2.3250 mL
15 mM 0.0620 mL 0.3100 mL 0.6200 mL 1.5500 mL
20 mM 0.0465 mL 0.2325 mL 0.4650 mL 1.1625 mL
25 mM 0.0372 mL 0.1860 mL 0.3720 mL 0.9300 mL
30 mM 0.0310 mL 0.1550 mL 0.3100 mL 0.7750 mL
40 mM 0.0232 mL 0.1162 mL 0.2325 mL 0.5812 mL
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HO-PEG24-OH Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HO-PEG24-OH2243942-52-9PROTAC LinkersInhibitorinhibitorinhibit

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