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  3. Hordenine-d6

Hordenine-d6  (Synonyms: Ordenina-d6; Peyocactine-d6)

Cat. No.: HY-N0113S Purity: 98.03%
SDS COA Handling Instructions

Hordenine-d6 (Ordenina-d6) is the deuterium labeled Hordenine. Hordenine, an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production.

For research use only. We do not sell to patients.

Hordenine-d<sub>6</sub> Chemical Structure

Hordenine-d6 Chemical Structure

CAS No. : 1346598-66-0

Size Price Stock Quantity
1 mg USD 95 In-stock
5 mg USD 230 In-stock
10 mg USD 370 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Hordenine-d6 (Ordenina-d6) is the deuterium labeled Hordenine. Hordenine, an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

171.27

Formula

C10H9D6NO

CAS No.
Unlabeled CAS

539-15-1

Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([2H])N(C([2H])([2H])[2H])CCC1=CC=C(C=C1)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMF : ≥ 25 mg/mL (145.97 mM)

DMF : ≥ 25 mg/mL (145.97 mM)

DMSO : ≥ 20 mg/mL (116.77 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : ≥ 20 mg/mL (116.77 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Ethanol : ≥ 5 mg/mL (29.19 mM)

Ethanol : ≥ 5 mg/mL (29.19 mM)

DMF:PBS(pH 7.2)(1:1) : ≥ 0.5 mg/mL (2.92 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.8387 mL 29.1937 mL 58.3873 mL
5 mM 1.1677 mL 5.8387 mL 11.6775 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMF:PBS(pH 7.2)(1:1) / Ethanol / Ethanol / DMSO / DMSO / DMF / DMF 1 mM 5.8387 mL 29.1937 mL 58.3873 mL 145.9684 mL
Ethanol / Ethanol / DMSO / DMSO / DMF / DMF 5 mM 1.1677 mL 5.8387 mL 11.6775 mL 29.1937 mL
10 mM 0.5839 mL 2.9194 mL 5.8387 mL 14.5968 mL
15 mM 0.3892 mL 1.9462 mL 3.8925 mL 9.7312 mL
20 mM 0.2919 mL 1.4597 mL 2.9194 mL 7.2984 mL
25 mM 0.2335 mL 1.1677 mL 2.3355 mL 5.8387 mL
DMSO / DMSO / DMF / DMF 30 mM 0.1946 mL 0.9731 mL 1.9462 mL 4.8656 mL
40 mM 0.1460 mL 0.7298 mL 1.4597 mL 3.6492 mL
50 mM 0.1168 mL 0.5839 mL 1.1677 mL 2.9194 mL
60 mM 0.0973 mL 0.4866 mL 0.9731 mL 2.4328 mL
80 mM 0.0730 mL 0.3649 mL 0.7298 mL 1.8246 mL
100 mM 0.0584 mL 0.2919 mL 0.5839 mL 1.4597 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Hordenine-d6
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