2. MAPK/ERK Pathway
  3. MAP4K
  4. HPK1-IN-37

HPK1-IN-37 (compound A85) is an inhibitor of HPK1 (IC50=3.7 nM). HPK1-IN-37 can be used for research in HPK1 related disorders or diseases including cancers.

For research use only. We do not sell to patients.

HPK1-IN-37 Chemical Structure

HPK1-IN-37 Chemical Structure

CAS No. : 2766481-68-7

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HPK1-IN-37 Related Antibodies

Top Publications Citing Use of Products

View All MAP4K Isoform Specific Products:

View All Isoforms
MAP4K2/GCK MAP4K3/GLK MAP4K4/HGK MAP4K5/KHS1 MAP4K6/MINK1 MAP4K7/TNIK MAP4K1/HPK1

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Description

HPK1-IN-37 (compound A85) is an inhibitor of HPK1 (IC50=3.7 nM). HPK1-IN-37 can be used for research in HPK1 related disorders or diseases including cancers[1].

IC50 & Target

IC50: 3.7 nM (MAP4K1/HPK1)[1]
Molecular Weight

521.61

Formula

C27H35N7O4
CAS No.
SMILES

CN(CC1)CCC1N(N=C2)C=C2OC(N=C3C4=CC(C5(O)COC5)=CC(N6[C@@H](CCC6)CO)=C4)=C(N=C3)N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HPK1-IN-37 Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HPK1-IN-372766481-68-7MAP4KMAPK Kinase Kinase Kinasepyrazolyloxypyrazinamine preparationHPK1 inhibitorInhibitorinhibitorinhibit

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HPK1-IN-37
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HY-156508
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