2. MAPK/ERK Pathway
  3. MAP4K
  4. HPK1-IN-49

HPK1-IN-49 (Compound I-4) is an inhibitor for hematopoietic progenitor kinase 1 (HPK1) with an IC50 >100 nM.

For research use only. We do not sell to patients.

HPK1-IN-49 Chemical Structure

HPK1-IN-49 Chemical Structure

CAS No. : 2845144-97-8

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HPK1-IN-49 Related Antibodies

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MAP4K2/GCK MAP4K3/GLK MAP4K4/HGK MAP4K5/KHS1 MAP4K6/MINK1 MAP4K7/TNIK MAP4K1/HPK1

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Description

HPK1-IN-49 (Compound I-4) is an inhibitor for hematopoietic progenitor kinase 1 (HPK1) with an IC50 >100 nM[1].

IC50 & Target

HPK1

 

Molecular Weight

500.57

Formula

C28H29FN6O2
CAS No.
SMILES

O=C(NC1)C2=C1C(C3=CN=C4C=C(F)C=CN43)=CN=C2NC5=CC=C(N6CCC[C@H](C(C)(C)O)C6)C=C5
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HPK1-IN-49 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HPK1-IN-492845144-97-8MAP4KMAPK Kinase Kinase KinaseInhibitorinhibitorinhibit

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