1. Epigenetics
  2. MicroRNA
  3. hsa-let-7b-5p agomir

hsa-let-7b-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

For research use only. We do not sell to patients.

RNA, (UGAGGUAGUAGGUUGUGUGGUU), complex with RNA, (CCACACAACCUACUACCUCANN) (1:1) (with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification)

hsa-let-7b-5p agomir Chemical Structure

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5 nmol USD 225 Get quote 1-2 weeks 1-2 weeks 1-2 weeks
20 nmol USD 450 Get quote 1-2 weeks 1-2 weeks 1-2 weeks
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Based on 1 publication(s) in Google Scholar

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Description

hsa-let-7b-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

Molecular Weight

15119.38

miRBase Accession Number
Mature miRNA Sequence

UGAGGUAGUAGGUUGUGUGGUU

Stem-loop ID

hsa-let-7b

Stem-loop Sequence

CGGGGUGAGGUAGUAGGUUGUGUGGUUUCAGGGCAGUGAUGUUGCCCCUCGGAAGAUAACUAUACAACCUACUGCCUUCCCUG

Species

Human, Mouse, Rat, Alligator mississippiensis, Astatotilapia burtoni, Bovine, Callithrix jacchus, Chicken, Chrysemys picta, Cricetulus griseus, Cyprinus carpio, Dasypus novemcinctus, Daubentonia madagascariensis, Dog, Fugu rubripes, Goat, Guinea pig, Metriaclima zebra, Microcebus murinus, Monodelphis domestica, Neolamprologus brichardi, Ophiophagus hannah, Oreochromis niloticus, Ornithorhynchus anatinus, Otolemur garnettii, Pan paniscus, Pan troglodytes, Papio hamadryas, Paralichthys olivaceus, Pongo pygmaeus, Pundamilia nyererei, Python bivittatus, Rabbit, Rhesus monkey, Saimiri boliviensis, Salmo salar, Taeniopygia guttata, Tetraodon nigroviridis, Zebrafish

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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hsa-let-7b-5p agomir Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
hsa-let-7b-5p agomir
Cat. No.:
HY-R00005A
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