1. Epigenetics
  2. MicroRNA
  3. hsa-miR-1249-3p agomir

hsa-miR-1249-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

For research use only. We do not sell to patients.

RNA, (ACGCCCUUCCCCCCCUUCUUCA), complex with RNA, (AAGAAGGGGGGGAAGGGCGUNN) (1:1) (with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification)

hsa-miR-1249-3p agomir Chemical Structure

Size Price Stock Quantity
5 nmol USD 225 Get quote 1-2 weeks 1-2 weeks 1-2 weeks
20 nmol USD 450 Get quote 1-2 weeks 1-2 weeks 1-2 weeks
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Based on 1 publication(s) in Google Scholar

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Description

hsa-miR-1249-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

Molecular Weight

15186.47

miRBase Accession Number
Mature miRNA Sequence

ACGCCCUUCCCCCCCUUCUUCA

Stem-loop ID

hsa-mir-1249

Stem-loop Sequence

GGGAGGAGGGAGGAGAUGGGCCAAGUUCCCUCUGGCUGGAACGCCCUUCCCCCCCUUCUUCACCUG

Species

Human, Mouse, Rat, Bovine, Cricetulus griseus, Dasypus novemcinctus, Dog, Eptesicus fuscus, Goat, Gorilla gorilla, Pan troglodytes, Pig, Pongo pygmaeus, Rabbit, Rhesus monkey

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
hsa-miR-1249-3p agomir
Cat. No.:
HY-R00148A
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