2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Histamine Receptor
  4. HTMT dimaleate

HTMT (dimaleate) is a potent histamine H1 and H2 receptor agonist. HTMT (dimaleate) is 4 x 104 times more active than histamine in H2-mediated effects in natural suppressor cells.

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HTMT dimaleate Chemical Structure

HTMT dimaleate Chemical Structure

CAS No. : 195867-54-0

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1 mg USD 35 In-stock
5 mg USD 110 In-stock
10 mg USD 165 In-stock
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Based on 1 publication(s) in Google Scholar

HTMT dimaleate Related Antibodies

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Description

HTMT (dimaleate) is a potent histamine H1 and H2 receptor agonist. HTMT (dimaleate) is 4 x 104 times more active than histamine in H2-mediated effects in natural suppressor cells[1].

IC50 & Target

H1 Receptor

 

H2 Receptor

 

Molecular Weight

614.57

Formula

C27H33F3N4O9
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(NCCC1=CN=CN1)CCCCC(NC2=CC=C(C(F)(F)F)C=C2)=O.O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (203.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6272 mL 8.1358 mL 16.2715 mL
5 mM 0.3254 mL 1.6272 mL 3.2543 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6272 mL 8.1358 mL 16.2715 mL 40.6788 mL
5 mM 0.3254 mL 1.6272 mL 3.2543 mL 8.1358 mL
10 mM 0.1627 mL 0.8136 mL 1.6272 mL 4.0679 mL
15 mM 0.1085 mL 0.5424 mL 1.0848 mL 2.7119 mL
20 mM 0.0814 mL 0.4068 mL 0.8136 mL 2.0339 mL
25 mM 0.0651 mL 0.3254 mL 0.6509 mL 1.6272 mL
30 mM 0.0542 mL 0.2712 mL 0.5424 mL 1.3560 mL
40 mM 0.0407 mL 0.2034 mL 0.4068 mL 1.0170 mL
50 mM 0.0325 mL 0.1627 mL 0.3254 mL 0.8136 mL
60 mM 0.0271 mL 0.1356 mL 0.2712 mL 0.6780 mL
80 mM 0.0203 mL 0.1017 mL 0.2034 mL 0.5085 mL
100 mM 0.0163 mL 0.0814 mL 0.1627 mL 0.4068 mL
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HTMT dimaleate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HTMT dimaleate195867-54-0Histamine ReceptorInhibitorinhibitorinhibit

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