2. Immunology/Inflammation Vitamin D Related/Nuclear Receptor
  3. Glucocorticoid Receptor
  4. Hydrocortisone aceponate

Hydrocortisone aceponate  (Synonyms: Hydrocortisone 17-propionate 21-acetate)

Cat. No.: HY-116691 Purity: 99.43%
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Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is a potent topical glucocorticoid. Hydrocortisone aceponate can be used for various dermatoses research.

For research use only. We do not sell to patients.

Hydrocortisone aceponate Chemical Structure

Hydrocortisone aceponate Chemical Structure

CAS No. : 74050-20-7

Size Price Stock Quantity
5 mg USD 50 In-stock
10 mg USD 70 In-stock
25 mg USD 125 In-stock
50 mg USD 195 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Hydrocortisone aceponate:

Hydrocortisone aceponate Related Antibodies

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Description

Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is a potent topical glucocorticoid. Hydrocortisone aceponate can be used for various dermatoses research[1].

Molecular Weight

460.56

Formula

C26H36O7
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](OC(CC)=O)(CC[C@]1([C@@]3(CCC4=CC(CC[C@@]4([C@]3([C@H](C2)O)[H])C)=O)[H])[H])C(COC(C)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (217.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1713 mL 10.8563 mL 21.7127 mL
5 mM 0.4343 mL 2.1713 mL 4.3425 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1713 mL 10.8563 mL 21.7127 mL 54.2817 mL
5 mM 0.4343 mL 2.1713 mL 4.3425 mL 10.8563 mL
10 mM 0.2171 mL 1.0856 mL 2.1713 mL 5.4282 mL
15 mM 0.1448 mL 0.7238 mL 1.4475 mL 3.6188 mL
20 mM 0.1086 mL 0.5428 mL 1.0856 mL 2.7141 mL
25 mM 0.0869 mL 0.4343 mL 0.8685 mL 2.1713 mL
30 mM 0.0724 mL 0.3619 mL 0.7238 mL 1.8094 mL
40 mM 0.0543 mL 0.2714 mL 0.5428 mL 1.3570 mL
50 mM 0.0434 mL 0.2171 mL 0.4343 mL 1.0856 mL
60 mM 0.0362 mL 0.1809 mL 0.3619 mL 0.9047 mL
80 mM 0.0271 mL 0.1357 mL 0.2714 mL 0.6785 mL
100 mM 0.0217 mL 0.1086 mL 0.2171 mL 0.5428 mL
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Hydrocortisone aceponate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hydrocortisone aceponate74050-20-7Hydrocortisone 17-propionate 21-acetateGlucocorticoid ReceptorInhibitorinhibitorinhibit

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