2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Hypoxanthine-d4

Hypoxanthine-d4 is the deuterium labeled Hypoxanthine[1]. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia[2].

For research use only. We do not sell to patients.

Hypoxanthine-d<sub>4</sub> Chemical Structure

Hypoxanthine-d4 Chemical Structure

CAS No. : 2483831-32-7

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Based on 1 publication(s) in Google Scholar

Other Forms of Hypoxanthine-d4:

Hypoxanthine-d4 Related Antibodies

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Description

Hypoxanthine-d4 is the deuterium labeled Hypoxanthine[1]. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Hypoxanthine-d4 Related Antibodies
Molecular Weight

140.14

Formula

C5D4N4O
CAS No.
Unlabeled CAS

68-94-0
Appearance

Solid

Color

White to off-white

SMILES

O=C1C2=C(N=C([2H])N2[2H])N([2H])C([2H])=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (71.36 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.1357 mL 35.6786 mL 71.3572 mL
5 mM 1.4271 mL 7.1357 mL 14.2714 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 7.1357 mL 35.6786 mL 71.3572 mL 178.3930 mL
5 mM 1.4271 mL 7.1357 mL 14.2714 mL 35.6786 mL
10 mM 0.7136 mL 3.5679 mL 7.1357 mL 17.8393 mL
15 mM 0.4757 mL 2.3786 mL 4.7571 mL 11.8929 mL
20 mM 0.3568 mL 1.7839 mL 3.5679 mL 8.9197 mL
25 mM 0.2854 mL 1.4271 mL 2.8543 mL 7.1357 mL
30 mM 0.2379 mL 1.1893 mL 2.3786 mL 5.9464 mL
40 mM 0.1784 mL 0.8920 mL 1.7839 mL 4.4598 mL
50 mM 0.1427 mL 0.7136 mL 1.4271 mL 3.5679 mL
60 mM 0.1189 mL 0.5946 mL 1.1893 mL 2.9732 mL
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Hypoxanthine-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hypoxanthine-d42483831-32-7Endogenous MetaboliteInhibitorinhibitorinhibit

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