2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. ICG-alkyne

ICG-alkyne is a click chemistry reagent containing an azide group.

For research use only. We do not sell to patients.

ICG-alkyne Chemical Structure

ICG-alkyne Chemical Structure

CAS No. : 1622335-41-4

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ICG-alkyne Related Antibodies

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Description

ICG-alkyne is a click chemistry reagent containing an azide group[1].

Molecular Weight

768.02

Formula

C48H53N3O4S
CAS No.
Appearance

Solid

Color

Brown to black

SMILES

O=C(CCCCCN1C2=C(C(C)(C)/C1=C\C=C\C=C\C=C\C3=[N+](CCCCS(=O)([O-])=O)C4=C(C3(C)C)C5=C(C=CC=C5)C=C4)C6=C(C=CC=C6)C=C2)NCC#C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (260.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3020 mL 6.5102 mL 13.0205 mL
5 mM 0.2604 mL 1.3020 mL 2.6041 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3020 mL 6.5102 mL 13.0205 mL 32.5512 mL
5 mM 0.2604 mL 1.3020 mL 2.6041 mL 6.5102 mL
10 mM 0.1302 mL 0.6510 mL 1.3020 mL 3.2551 mL
15 mM 0.0868 mL 0.4340 mL 0.8680 mL 2.1701 mL
20 mM 0.0651 mL 0.3255 mL 0.6510 mL 1.6276 mL
25 mM 0.0521 mL 0.2604 mL 0.5208 mL 1.3020 mL
30 mM 0.0434 mL 0.2170 mL 0.4340 mL 1.0850 mL
40 mM 0.0326 mL 0.1628 mL 0.3255 mL 0.8138 mL
50 mM 0.0260 mL 0.1302 mL 0.2604 mL 0.6510 mL
60 mM 0.0217 mL 0.1085 mL 0.2170 mL 0.5425 mL
80 mM 0.0163 mL 0.0814 mL 0.1628 mL 0.4069 mL
100 mM 0.0130 mL 0.0651 mL 0.1302 mL 0.3255 mL
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ICG-alkyne Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ICG-alkyne1622335-41-4ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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