2. Vitamin D Related/Nuclear Receptor
  3. VD/VDR
  4. Impurity C of Alfacalcidol

Impurity of Alfacalcidol. Alfacalcidol (1-hydroxycholecalciferol; Alpha D3; 1.alpha.-Hydroxyvitamin D3) is a non-selective VDR activator medication.

For research use only. We do not sell to patients.

Impurity C of Alfacalcidol Chemical Structure

Impurity C of Alfacalcidol Chemical Structure

CAS No. : 82266-85-1

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1 mg USD 420 In-stock
5 mg USD 950 In-stock
10 mg USD 1550 In-stock
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100 mg   Get quote  

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Impurity C of Alfacalcidol Related Antibodies

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Description

Impurity of Alfacalcidol. Alfacalcidol (1-hydroxycholecalciferol; Alpha D3; 1.alpha.-Hydroxyvitamin D3) is a non-selective VDR activator medication. IC50 value: Target: VDR activator Alfacalcidol (1-hydroxycholecalciferol; Alpha D3; 1.alpha.-Hydroxyvitamin D3) improves mechanical bone strength and bone mass; suppresses osteoclastic bone resorption in vivo.

Molecular Weight

575.78

Formula

C35H49N3O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@@H]1CC(C2C=C3[C@@](CC[C@@H]4[C@@H](CCCC(C)C)C)([H])[C@]4(C)CCC3N(C(N5C6=CC=CC=C6)=O)N2C5=O)=C(C)[C@@H](O)C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 6.67 mg/mL (11.58 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7368 mL 8.6839 mL 17.3677 mL
5 mM 0.3474 mL 1.7368 mL 3.4735 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.81%

COA (254 KB) HNMR (203 KB) LCMS (403 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7368 mL 8.6839 mL 17.3677 mL 43.4194 mL
5 mM 0.3474 mL 1.7368 mL 3.4735 mL 8.6839 mL
10 mM 0.1737 mL 0.8684 mL 1.7368 mL 4.3419 mL
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Impurity C of Alfacalcidol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Impurity C of Alfacalcidol82266-85-1VD/VDRVitamin DVitamin D receptorInhibitorinhibitorinhibit

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