1. Others Anti-infection Metabolic Enzyme/Protease
  2. Isotope-Labeled Compounds HIV HIV Protease
  3. Indinavir-d6

Indinavir-d6  (Synonyms: MK-639-d6 free base; L-735524-d6 free base)

Cat. No.: HY-B0689S
Handling Instructions

Indinavir-d6 is the deuterium labeled Indinavir. Indinavir (MK-639; L735524) is a potent and specific HIV protease inhibitor that appears to have good oral bioavailability.

For research use only. We do not sell to patients.

Indinavir-d<sub>6</sub> Chemical Structure

Indinavir-d6 Chemical Structure

CAS No. : 185897-02-3

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Description

Indinavir-d6 is the deuterium labeled Indinavir. Indinavir (MK-639; L735524) is a potent and specific HIV protease inhibitor that appears to have good oral bioavailability.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

619.83

Formula

C36H41D6N5O4

CAS No.
Unlabeled CAS

150378-17-9

SMILES

CC(C)(C)NC([C@H](CN(CC1)C([2H])([2H])C2=C([2H])N=C([2H])C([2H])=C2[2H])N1C[C@@H](O)C[C@@H](CC3=CC=CC=C3)C(N[C@H]4C5=CC=CC=C5C[C@H]4O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Indinavir-d6
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HY-B0689S
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