Indole-3-pyruvic acid-d₅

Name: Indole-3-pyruvic acid-d 5
Brand: MedChemExpress
SKU: HY-W718300
Rating: 4.5 (1 reviews)

Cat. No.: HY-W718300 Purity: 95.00%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Indole-3-pyruvic acid-d₅ is deuterated labeled Indole-3-pyruvic acid. Indole-3-pyruvic acid, a keto analogue of tryptophan, is an orally active AHR agonist. Indole-3-pyruvic acid has antioxidant properties, and can be used in the research of inflammation, anxiety.

For research use only. We do not sell to patients.

Indole-3-pyruvic acid-d<sub>5</sub> Chemical Structure

Indole-3-pyruvic acid-d₅ Chemical Structure

CAS No. : 85163-57-1

Size	Price	Stock	Quantity
500 μg	USD 370	In-stock	Estimated Time of Arrival: December 31

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Based on 1 publication(s) in Google Scholar

Other Forms of Indole-3-pyruvic acid-d₅:

Indole-3-pyruvic acid Get quote

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Biological Activity
Purity & Documentation
References
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Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

208.22

Formula

C₁₁H₄D₅NO₃

CAS No.

85163-57-1

Appearance

Solid

Color

Light yellow to yellow

SMILES

[2H]C1=C(CC(C(O)=O)=O)C2=C(N1)C([2H])=C([2H])C([2H])=C2[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

H₂O : 20 mg/mL (96.05 mM; Need ultrasonic and warming)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.8026 mL	24.0131 mL	48.0261 mL
5 mM	0.9605 mL	4.8026 mL	9.6052 mL
10 mM	0.4803 mL	2.4013 mL	4.8026 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 95.00%

Select Batch:

Data Sheet (275 KB) SDS (393 KB)

COA (255 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	4.8026 mL	24.0131 mL	48.0261 mL	120.0653 mL
	5 mM	0.9605 mL	4.8026 mL	9.6052 mL	24.0131 mL
	10 mM	0.4803 mL	2.4013 mL	4.8026 mL	12.0065 mL
	15 mM	0.3202 mL	1.6009 mL	3.2017 mL	8.0044 mL
	20 mM	0.2401 mL	1.2007 mL	2.4013 mL	6.0033 mL
	25 mM	0.1921 mL	0.9605 mL	1.9210 mL	4.8026 mL
	30 mM	0.1601 mL	0.8004 mL	1.6009 mL	4.0022 mL
	40 mM	0.1201 mL	0.6003 mL	1.2007 mL	3.0016 mL
	50 mM	0.0961 mL	0.4803 mL	0.9605 mL	2.4013 mL
	60 mM	0.0800 mL	0.4002 mL	0.8004 mL	2.0011 mL
	80 mM	0.0600 mL	0.3002 mL	0.6003 mL	1.5008 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.