2. Anti-infection
  3. Influenza Virus
  4. Influenza virus-IN-1

Influenza virus-IN-1 (compound 14) is a potent influenza A virus inhibitor with an EC50 of 2.46 µM and CC50 of >200 µM. Influenza virus-IN-1 shows a concentration dependent inhibition activity for PAN endonuclease with EC50 of 312.36 nM. Influenza virus-IN-1 shows shows anti-influenza A virus activities.

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Influenza virus-IN-1 Chemical Structure

Influenza virus-IN-1 Chemical Structure

CAS No. : 108729-21-1

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Influenza virus-IN-1 Related Antibodies

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Description

Influenza virus-IN-1 (compound 14) is a potent influenza A virus inhibitor with an EC50 of 2.46 µM and CC50 of >200 µM. Influenza virus-IN-1 shows a concentration dependent inhibition activity for PAN endonuclease with EC50 of 312.36 nM. Influenza virus-IN-1 shows shows anti-influenza A virus activities[1].

IC50 & Target

EC50: 2.46 µM (influenza virus); CC50: >200 µM (influenza virus)[1]
Cellular Effect
Cell Line Type Value Description References
MDCK CC50
> 200 μM
Compound: 14
Cytotoxicity against dog MDCK cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against dog MDCK cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
[PMID: 31954881]
Molecular Weight

303.31

Formula

C16H17NO5
CAS No.
SMILES

O=C(NCCC1=CC=C(O)C(O)=C1)CC2=CC=C(O)C(O)=C2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Influenza virus-IN-1 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Influenza virus-IN-1108729-21-1Influenza VirusMDCK cellsanti-IAV activityPAN endonucleaseInhibitorinhibitorinhibit

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