2. Anti-infection
  3. Bacterial
  4. Irloxacin

Irloxacin  (Synonyms: Pirfloxacin)

Cat. No.: HY-105033 Purity: 98.49%
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Irloxacin (Pirfloxacin) is a quinolone antibacterial agent. Irloxacin shows greater activity with an acid pH. Irloxacin has a good in vitro antimicrobial spectrum against both gram-positive and gram-negative bacteria. Orally active.

For research use only. We do not sell to patients.

Irloxacin Chemical Structure

Irloxacin Chemical Structure

CAS No. : 91524-15-1

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 330 In-stock
Solution
10 mM * 1 mL in DMSO USD 330 In-stock
Solid
5 mg USD 300 In-stock
10 mg USD 480 In-stock
25 mg USD 950 In-stock
50 mg USD 1450 In-stock
100 mg USD 2250 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Irloxacin Related Antibodies

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Description

Irloxacin (Pirfloxacin) is a quinolone antibacterial agent. Irloxacin shows greater activity with an acid pH. Irloxacin has a good in vitro antimicrobial spectrum against both gram-positive and gram-negative bacteria. Orally active[1].

Molecular Weight

300.28

Formula

C16H13FN2O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCN1C2=CC(N3C=CC=C3)=C(F)C=C2C(C(C(O)=O)=C1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 33.33 mg/mL (111.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3302 mL 16.6511 mL 33.3022 mL
5 mM 0.6660 mL 3.3302 mL 6.6605 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3302 mL 16.6511 mL 33.3023 mL 83.2556 mL
5 mM 0.6660 mL 3.3302 mL 6.6605 mL 16.6511 mL
10 mM 0.3330 mL 1.6651 mL 3.3302 mL 8.3256 mL
15 mM 0.2220 mL 1.1101 mL 2.2202 mL 5.5504 mL
20 mM 0.1665 mL 0.8326 mL 1.6651 mL 4.1628 mL
25 mM 0.1332 mL 0.6660 mL 1.3321 mL 3.3302 mL
30 mM 0.1110 mL 0.5550 mL 1.1101 mL 2.7752 mL
40 mM 0.0833 mL 0.4163 mL 0.8326 mL 2.0814 mL
50 mM 0.0666 mL 0.3330 mL 0.6660 mL 1.6651 mL
60 mM 0.0555 mL 0.2775 mL 0.5550 mL 1.3876 mL
80 mM 0.0416 mL 0.2081 mL 0.4163 mL 1.0407 mL
100 mM 0.0333 mL 0.1665 mL 0.3330 mL 0.8326 mL
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Irloxacin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Irloxacin91524-15-1PirfloxacinBacterialantibacterial agentacid pHgram-positivegram-negative bacteriaoralInhibitorinhibitorinhibit

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