1. Anti-infection
  2. HIV
  3. Isoapetalic acid

Isoapetalic acid (compound 4) is a potent anti-HIV agent.

For research use only. We do not sell to patients.

Isoapetalic acid Chemical Structure

Isoapetalic acid Chemical Structure

CAS No. : 34366-34-2

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Description

Isoapetalic acid (compound 4) is a potent anti-HIV agent[1].

Cellular Effect
Cell Line Type Value Description References
RAW264.7 CC50
663.17 μM
Compound: 14
Cytotoxicity against mouse RAW264.7 cells assessed as effect on cell viability measured after 12 hrs by MTT assay
Cytotoxicity against mouse RAW264.7 cells assessed as effect on cell viability measured after 12 hrs by MTT assay
[PMID: 35503996]
RAW264.7 IC50
8.44 μM
Compound: 14
Antiinflammatory activity in mouse RAW264.7 assessed as inhibition of LPS-induced NO production preincubated for 12 hrs followed by LPS stimulation and measured after 6 hrs by Griess reagent based assay
Antiinflammatory activity in mouse RAW264.7 assessed as inhibition of LPS-induced NO production preincubated for 12 hrs followed by LPS stimulation and measured after 6 hrs by Griess reagent based assay
[PMID: 35503996]
In Vitro

Isoapetalic acid (compound 4) shows anti-HIV activity with an inhibition rate of 20.6 for HIV-1 RT[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

388.45

Formula

C22H28O6

CAS No.
SMILES

OC(C[C@H](C1=C2C(C([C@@H](C)[C@H](C)O2)=O)=C(O)C3=C1OC(C)(C)C=C3)CCC)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Isoapetalic acid
Cat. No.:
HY-N4004
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