2. Others
  3. Fluorescent Dye
  4. Isoindigo

Isoindigo is the acceptor of donor-acceptor (D-A) conjugated polymer, as well as an Indigo series dye. Isoindigo equips two lactam rings and strong electron-withdrawing character. Isoindigo can be used for dyeing and pigment preparation. Isoindigo shows high mobility and good ambient stability in FETs.

For research use only. We do not sell to patients.

Isoindigo Chemical Structure

Isoindigo Chemical Structure

CAS No. : 476-34-6

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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10 mM * 1 mL in DMSO In-stock
Solid
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Based on 1 publication(s) in Google Scholar

Isoindigo Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

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Description

Isoindigo is the acceptor of donor-acceptor (D-A) conjugated polymer, as well as an Indigo series dye. Isoindigo equips two lactam rings and strong electron-withdrawing character. Isoindigo can be used for dyeing and pigment preparation. Isoindigo shows high mobility and good ambient stability in FETs[1].

Cellular Effect
Cell Line Type Value Description References
HCT-116 IC50
> 30 μM
Compound: 1
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
[PMID: 19783149]
HL-60 IC50
16.6 μM
Compound: 1
Antiproliferative activity against human HL60 cells after 5 days by MTT assay
Antiproliferative activity against human HL60 cells after 5 days by MTT assay
[PMID: 19783149]
Huh-7 IC50
28.9 μM
Compound: 1
Antiproliferative activity against human HuH7 cells after 72 hrs by MTT assay
Antiproliferative activity against human HuH7 cells after 72 hrs by MTT assay
[PMID: 19783149]
IMR-90 IC50
16.3 μM
Compound: 1
Antiproliferative activity against human IMR90 cells after 72 hrs by MTT assay
Antiproliferative activity against human IMR90 cells after 72 hrs by MTT assay
[PMID: 19783149]
K562 IC50
6.7 μM
Compound: 1
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
[PMID: 19783149]
KB IC50
1.6 μM
Compound: isoindigo
Antiproliferative activity against human KB cells after 72 hrs by MTS test
Antiproliferative activity against human KB cells after 72 hrs by MTS test
[PMID: 17628214]
Molecular Weight

262.27

Formula

C16H10N2O2
CAS No.
Appearance

Solid

Color

Brown to reddish brown

SMILES

O=C1NC2=C(C=CC=C2)/C1=C3C(NC4=C\3C=CC=C4)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (95.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8129 mL 19.0645 mL 38.1289 mL
5 mM 0.7626 mL 3.8129 mL 7.6258 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.8129 mL 19.0645 mL 38.1289 mL 95.3223 mL
5 mM 0.7626 mL 3.8129 mL 7.6258 mL 19.0645 mL
10 mM 0.3813 mL 1.9064 mL 3.8129 mL 9.5322 mL
15 mM 0.2542 mL 1.2710 mL 2.5419 mL 6.3548 mL
20 mM 0.1906 mL 0.9532 mL 1.9064 mL 4.7661 mL
25 mM 0.1525 mL 0.7626 mL 1.5252 mL 3.8129 mL
30 mM 0.1271 mL 0.6355 mL 1.2710 mL 3.1774 mL
40 mM 0.0953 mL 0.4766 mL 0.9532 mL 2.3831 mL
50 mM 0.0763 mL 0.3813 mL 0.7626 mL 1.9064 mL
60 mM 0.0635 mL 0.3177 mL 0.6355 mL 1.5887 mL
80 mM 0.0477 mL 0.2383 mL 0.4766 mL 1.1915 mL
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Isoindigo Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Isoindigo476-34-6Fluorescent DyeInhibitorinhibitorinhibit

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